57777-97-6

Usage

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Neuraminic Acid derivative.

Upstream product

• 19342-75-7 methyl (benzyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosid)onate 
• 100-51-6 benzyl alcohol 
• 67670-69-3 N-acetyl-4,7,8,9-tetra-O-acetyl-2-chloro-2-deoxyneuraminic acid methyl ester 

Downstream Products

• 860783-42-2 (2R,4S,5R,6R)-5-(Acetyl-tert-butoxycarbonyl-amino)-4-benzoyloxy-2-benzyloxy-6-((4S,5R)-5-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 860783-39-7 (2R,4S,5R,6R)-4-Benzoyloxy-2-benzyloxy-6-((1R,2R)-3-benzyloxy-1,2-dihydroxy-propyl)-5-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 860783-43-3 (2R,4S,5R,6R)-4-Benzoyloxy-2-benzyloxy-6-((4S,5R)-5-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-5-tert-butoxycarbonylamino-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 860783-38-6 (2R,4S,5R,6R)-5-Acetylamino-4-benzoyloxy-2-benzyloxy-6-((1R,2R)-3-benzyloxy-1,2-dihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 860783-41-1 (2R,4S,5R,6R)-5-Acetylamino-4-benzoyloxy-2-benzyloxy-6-((1R,2R)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 860783-40-0 (2R,4S,5R,6R)-5-Acetylamino-4-benzoyloxy-2-benzyloxy-6-[(S)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 146369-14-4 (2R,4S,5R,6R)-5-Acetylamino-2-benzyloxy-6-[(S)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-4-hydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of sialic acid derivatives as ligands for the myelin-associated glycoprotein (MAG)

The trisaccharide substructure 13 of the ganglioside GQ1bα shows a remarkable affinity for the myelin-associated glycoprotein (MAG). In the search for structurally simplified and pharmacokinetically improved mimics of 13, sialosides with modifications at

Enhanced sialylating activity of O-chloroacetylated 2-thioethyl sialosides

It has been shown that O-chloroacetyl protecting groups enhance significantly sialylating activity of 2-thioethyl sialosides in model reactions of α(2-8)-sialylation. Ethyl 4,7,8,9-tetra-O-chloroacetyl-3,5-dideoxy-2- thio-5-trifluoroacetamido-D-glycero-α-