193421-73-7

Basic information

• Product Name: Benzeneacetic acid, a-amino-a-2-propenyl-, ethyl ester
• CAS NO: 193421-73-7
• Molecular Formula: C13H17NO2
• Molecular Weight: 219.283
• Mol File: 193421-73-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, a-amino-a-2-propenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-amino-a-2-propenyl-, ethyl ester(193421-73-7)
• EPA Substance Registry System: Benzeneacetic acid, a-amino-a-2-propenyl-, ethyl ester(193421-73-7)

Safety Data

• Hazardous Substances Data: 193421-73-7(Hazardous Substances Data)

Upstream product

• 6097-58-1 ethyl 2-phenyl-2-aminoacetate 
• 142035-33-4 ethyl N-(phenylmethylene)glycinate 
• 2835-06-5 phenylglycin 
• 106-95-6 allyl bromide 

Downstream Products

• 847027-69-4 (2S)-4-(2,5-difluorophenyl)-N-[(4R,6S)-6-fluoro-1-methylazepan-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide 
• 847027-70-7 (2S)-4-(2,5-difluorophenyl)-N-[(4S,6R)-6-fluoro-1-methylazepan-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide 
• 152375-59-2 (R)-α-allyl-α-phenylglycine ethyl ester 
• 149118-38-7 (R)-2-Phenyl-2-(2-propenyl)glycin 
• 84570-47-8 (S)-2-amino-2-phenylpent-4-enoic acid 
• 144073-04-1 (RS)-2-amino-2-phenyl-4-penten-1-ol 
• 845256-48-6 (2S)-4-(2,5-difluorophenyl)-2-phenyl-2-[(1,1,2,2-tetramethylpropoxy)methyl]-2,5-dihydro-1H-pyrrole 

Relevant articles and documents

Mitotic kinesin inhibitors

The present invention relates to dihydropyrrole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention is also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

Highly enantioselective synthesis of β-amino alcohols

N,N-Dialkyl-β-amino alcohols derived from α-amino acids can be rearranged enantiospecifically by using TFAA/Et3N/NaOH to give 1,2-amino alcohols with enantiomeric excess up to 99%.