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Benzenecarboximidamide, N-(4-fluorophenyl)-4-(methylthio)-, is a chemical compound with the molecular formula C14H13FN2S. It is a derivative of carboximidamide, featuring a 4-fluorophenyl group and a methylthio group attached to the nitrogen atom. Benzenecarboximidamide, N-(4-fluorophenyl)-4-(methylthio)is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals, as well as for its biological activities, which are currently under investigation for medicinal uses in cancer treatment, antimicrobial therapy, and as an insecticide and fungicide.

193422-48-9

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193422-48-9 Usage

Uses

Used in Pharmaceutical Synthesis:
Benzenecarboximidamide, N-(4-fluorophenyl)-4-(methylthio)-, is used as an intermediate in the synthesis of pharmaceuticals for its potential medicinal applications. Its unique structure allows for the development of new drugs targeting various diseases.
Used in Agrochemical Synthesis:
Benzenecarboximidamide, N-(4-fluorophenyl)-4-(methylthio)is also utilized in the synthesis of agrochemicals, where it may contribute to the development of new pesticides or herbicides, enhancing agricultural productivity and crop protection.
Used in Cancer Treatment Research:
Benzenecarboximidamide, N-(4-fluorophenyl)-4-(methylthio)-, is being researched for its potential as a cancer treatment agent. Its biological activities suggest that it may have an impact on tumor growth and progression, warranting further investigation into its efficacy and safety in oncology.
Used in Antimicrobial Therapy Research:
Benzenecarboximidamide, N-(4-fluorophenyl)-4-(methylthio)is under study for its potential role in antimicrobial therapy, where it may contribute to the development of new antibiotics or antifungal agents, addressing the growing need for novel treatments against drug-resistant pathogens.
Used in Insecticidal and Fungicidal Applications:
Benzenecarboximidamide, N-(4-fluorophenyl)-4-(methylthio)-, has been studied for its potential insecticidal and fungicidal properties, which could be applied in agriculture to protect crops from pests and diseases, thereby increasing yield and quality.
Further research is necessary to fully understand the pharmacological and toxicological properties of Benzenecarboximidamide, N-(4-fluorophenyl)-4-(methylthio)-, to ensure its safe and effective use in these applications.

Check Digit Verification of cas no

The CAS Registry Mumber 193422-48-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,3,4,2 and 2 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 193422-48:
(8*1)+(7*9)+(6*3)+(5*4)+(4*2)+(3*2)+(2*4)+(1*8)=139
139 % 10 = 9
So 193422-48-9 is a valid CAS Registry Number.

193422-48-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N'-(4-fluorophenyl)-4-methylsulfanylbenzenecarboximidamide

1.2 Other means of identification

Product number -
Other names N-(4-fluorophenyl)-4-(methylthio)benzenecarboximidamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:193422-48-9 SDS

193422-48-9Relevant academic research and scientific papers

Novel pyrimidone derivatives

-

Page 11, (2008/06/13)

The present invention relates to novel pyrimidone derivatives of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable sa

Studies on anti-inflammatory agents. IV. Synthesis and pharmacological properties of 1,5-diarylpyrazoles and related derivatives

Tsuji, Kiyoshi,Nakamura, Katsuya,Konishi, Nobukiyo,Tojo, Takashi,Ochi, Takehiro,Senoh, Hachiro,Matsuo, Masaaki

, p. 987 - 995 (2007/10/03)

A series of novel 1,5-diarylpyrazole derivatives was synthesized and tested for anti-inflammatory and analgesic activities to develop anti- inflammatory agents with fewer side effects than existing nonsteroidal anti- inflammatory drugs. The structure-activity relationships in this series were extensively studied. Electron-withdrawing substituents such as CN and CF3 were optimal at the 3-position of the pyrazole ring. Replacement of these substituents with bulky ones gave less active compounds. The 4- (methylsulfonyl)phenyl group seemed to be the optimal group at the 5-position of the pyrazole ring. The most potent compound was 1-(4-fluorophenyl)-5-[4- (methylsulfonyl)phenyl]-pyrazole-3-carbonitrile (19a), with oral ED50 values of 0.030 and 0.47 mg/kg on adjuvant-induced arthritis and collagen- induced arthritis, respectively, and an ED30 value of 7.4 mg/kg in the yeast-induced hyperalgesia (Randall-Selitto) assay. Compound 19a also showed potent inducible cyclooxygenase (COX-2)-inhibitory activity (IC50=0.24μm) with no COX-1 inhibition even at 100μM.

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