193468-16-5Relevant academic research and scientific papers
An enantioselective total synthesis of (+)- and (-)-saudin. Determination of the absolute configuration
Boeckman Jr., Robert K.,Ferreira, Maria del Rosario Rico,Mitchell, Lorna H.,Shao, Pengcheng
, p. 190 - 191 (2002)
A short efficient enantioselective synthesis of both (+)- and (-)-saudin, a naturally occurring hypoglycemic diterpene, is described. This synthesis establishes the absolute configuration of natural (-)-saudin for the first time. The key steps include the
Asymmetric synthesis of glutamate derivatives
Seck, Rokhayatou,Gassama, Abdoulaye,Nour, Mohammed,Demange, Luc,Cavé, Christian
, p. 51 - 62 (2017/06/19)
Analogs of glutamic acid were synthesized through the asymmetric Michael reaction using chiral acyclic β-enaminoesters and various Michael acceptors. The influence of the alkoxy group of the enaminoesters and also the nature of the olefins in the presence
Michael reaction of acyclic β-enaminoesters derived from α-alkyl-β-ketoesters and chiral α-methylbenzylamine: Stereoselective generation of quaternary carbon centres
Maiti,Ghoshal,Mukhopadhyay,Achari,Banerjee
, p. 1072 - 1080 (2007/10/03)
Michael reaction of electrophilic olefins with acyclic β-enaminoester substrates derived from α-substituted β-ketoesters and (R)- or (S)-α-methylbenzylamine under neutral conditions resulted in the enantioselective formation of quaternary centres. The add
Condensation of chiral imines and chiral β-enaminoesters with maleic and citraconic anhydrides
Cave, Christian,Gassama, Abdoulaye,Mahuteau, Jacqueline,D'Angelo, Jean,Riche, Claude
, p. 4773 - 4776 (2007/10/03)
Condensations of chiral imines 1 and 4, and chiral enaminoesters 10 and 13, with maleic and citraconic anhydrides were reported. These experimental outcomes can be rationalized by invoking the compact, endo-approaches of the two reactions 18.
