193530-72-2Relevant articles and documents
Collective synthesis of natural products sharing the dihydro-γ-ionone core
Castillo, Alexis,Silva, Lucia,Briones, David,Quílez Del Moral, José F.,Barrero, Alejandro F.
, p. 3266 - 3273 (2015/05/20)
We decided to follow the so-called "collective total synthesis" approach to synthesize several structurally different molecules from a common intermediate possessing appropriate stereochemistry and functionalities. As the common precursor for the efficient preparation of these bioactive molecules, we chose (+)-3,4-dihydro-γ-ionone (1), a natural compound present in minor quantities in ambergris and in the plant Bellardia trixago. Thus, we report herein the enantioselective synthesis of siccanochromene F (2), metachromins U (3) and V (4), and bicyclic squalene derivative 5 as well as the formal syntheses of ambrein (6), phenazinomycin (7), and (-)-siccanin (8).
Total synthesis of phenazinomycin and its enantiomer via high-pressure reaction
Kinoshita, Yoshiharu,Kitahara, Takeshi
, p. 4993 - 4996 (2007/10/03)
Total synthesis of phenazinomycin a rare type of phenazine antibiotic, was achieved by using high pressure reaction. Chiral sesquiterpene moiety in the side chain was synthesized employing (S)-3-hydroxy-2,2- dimethylcyclohexanone as a chiral source.
