Cas 193534-43-9,1H-1,4-Benzodiazepine-2-acetic acid, 2,3,4,5-tetrahydro-4-methyl-7-[[[(5-methyl-1H-imidazo[4,5-b]pyridin-2-yl) methyl]amino]carbonyl]-3-oxo-, methyl ester, (S)-

193534-43-9

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Basic information

Product Name: 1H-1,4-Benzodiazepine-2-acetic acid, 2,3,4,5-tetrahydro-4-methyl-7-[[[(5-methyl-1H-imidazo[4,5-b]pyridin-2-yl) methyl]amino]carbonyl]-3-oxo-, methyl ester, (S)-
Synonyms:
CAS NO:193534-43-9
Molecular Formula: C22H24N6O4
Molecular Weight: 436.47
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 1H-1,4-Benzodiazepine-2-acetic acid, 2,3,4,5-tetrahydro-4-methyl-7-[[[(5-methyl-1H-imidazo[4,5-b]pyridin-2-yl) methyl]amino]carbonyl]-3-oxo-, methyl ester, (S)-(CAS DataBase Reference)
NIST Chemistry Reference: 1H-1,4-Benzodiazepine-2-acetic acid, 2,3,4,5-tetrahydro-4-methyl-7-[[[(5-methyl-1H-imidazo[4,5-b]pyridin-2-yl) methyl]amino]carbonyl]-3-oxo-, methyl ester, (S)-(193534-43-9)
EPA Substance Registry System: 1H-1,4-Benzodiazepine-2-acetic acid, 2,3,4,5-tetrahydro-4-methyl-7-[[[(5-methyl-1H-imidazo[4,5-b]pyridin-2-yl) methyl]amino]carbonyl]-3-oxo-, methyl ester, (S)-(193534-43-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 193534-43-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 193534-43-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,3,5,3 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 193534-43:
(8*1)+(7*9)+(6*3)+(5*5)+(4*3)+(3*4)+(2*4)+(1*3)=149
149 % 10 = 9
So 193534-43-9 is a valid CAS Registry Number.

193534-43-9Upstream product

33259-72-2 2,3-diamino-6-methyl-pyridine

193534-43-9Downstream Products

193534-43-9Relevant academic research and scientific papers

Discovery of an imidazopyridine-containing 1,4-benzodiazepine nonpeptide vitronectin receptor (αvβ3) antagonist with efficacy in a restenosis model

Keenan, Richard M.,Lago, M. Amparo,Miller, William H.,Ali, Fadia E.,Cousins, Russell D.,Hall, Leon B.,Hwang, Shing-Mei,Jakas, Dalia R.,Kwon, Chet,Louden, Calvert,Nguyen, Thomas T.,Ohlstein, Eliot H.,Rieman, David J.,Ross, Steven T.,Samanen, James M.,Smith, Brian R.,Stadel, Jeffrey,Takata, Dennis T.,Vickery, Lynne,Yuan, Catherine C. K.,Yue, Tian-Li

, p. 3171 - 3176 (1998)

In the 3-oxo-1,4-benzodiazepine-2-acetic acid series of vitronectin receptor (αvβ3) antagonists, a compound containing an imidazopyridine arginine mimetic was discovered which had sufficient potency and iv pharmacokinetics for demonstration of efficacy in a rat restenosis model.

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