193535-31-8Relevant academic research and scientific papers
First scale-up synthesis of FU-23, a novel water-soluble pleuromutilin-derived antibiotic
Fu, Liqiang,Liu, Xin,Cheng, Jianjun,He, Huili,Cai, Zhan,Guo, Xingsheng,Ding, Shi,Yang, Yushe
, p. 815 - 819 (2011/03/20)
A first scale-up synthesis of FU-23 (1), a potent and effective water-soluble pleuromutilin-derived antibiotic, is described. The original synthesis from the medicinal chemistry group provided 1 in seven steps and 10.9% overall yield, required four chroma
