193539-80-9Relevant articles and documents
Synthesis and spectral properties of 2-methylthio-3H-7-[(o-; m- and p-substituted)phenoxy]-4-(p-substituted-phenyl)-[1,5]benzodiazepines
Cortes, Eduardo Cortes,Romero, Cristina A. Cortes,Mellado, Olivia Garcia
, p. 1321 - 1324 (2002)
A series of eleven new 2-methylthio-3H-7-[(o-; m- and p-substituted) phenoxy]-4-(p-substituted-phenyl)-[1,5]benzodiazepines, which have potentially useful pharmacological activities, has been synthesized by condensing the 4-[(o-; m- and p-R1)phenoxy]-1,2-phenylendiamines with 3,3-dimercapto-l-(p-R2-phenyl)-2-propen-1-one. Afterward the 1H-[1,5]benzodiazepine-2-thiones obtained were treated with sodium hydride and methyl iodide. The structure of all products was corroborated by ir, 1H nmr, 13C nmr and ms.
Synthesis and spectral properties of 2,3-dihydro-4-(paramethylphenyl)- 7-[(o-, m-, and p-substituted)phenoxy]-1H-1,5-benzodiazepine-2-thiones
Cortes,Torres
, p. 953 - 956 (2007/10/03)
A series of twelve new 2,3-dihydro-4-(para-methylphenyl)-7-[(o-, m-, and p-substituted)phenoxy]-1H-1,5-benzodiazepine-2-thiones, which have potentially useful pharmacological properties, has been synthesized by condensing the 3,3-dimercapto-1-(p-methylphenyl)-2-propen-1-one with 3,4- diaminophenyl-R-phenyl ethers. The structure of all products was corroborated by ir; 1H-nmr; 13C-nmr and ms.