231956-18-6Relevant articles and documents
Synthesis and spectral properties of 2-methylthio-3H-7-[(o-; m- and p-substituted)phenoxy]-4-(p-substituted-phenyl)-[1,5]benzodiazepines
Cortes, Eduardo Cortes,Romero, Cristina A. Cortes,Mellado, Olivia Garcia
, p. 1321 - 1324 (2007/10/03)
A series of eleven new 2-methylthio-3H-7-[(o-; m- and p-substituted) phenoxy]-4-(p-substituted-phenyl)-[1,5]benzodiazepines, which have potentially useful pharmacological activities, has been synthesized by condensing the 4-[(o-; m- and p-R1)phenoxy]-1,2-phenylendiamines with 3,3-dimercapto-l-(p-R2-phenyl)-2-propen-1-one. Afterward the 1H-[1,5]benzodiazepine-2-thiones obtained were treated with sodium hydride and methyl iodide. The structure of all products was corroborated by ir, 1H nmr, 13C nmr and ms.