193635-15-3

Upstream product

• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 
• 2680-03-7 N,N-Dimethylacrylamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 193634-85-4 N,N-dimethyl-1-(4-methylbenzenesulfonyl)aziridine-2-carboxamide 

Downstream Products

• 227289-16-9 {(S)-3-[(2-Dimethylcarbamoyl-ethyl)-(toluene-4-sulfonyl)-amino]-1-methyl-2-oxo-propyl}-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Synthesis and testing of azaglutamine derivatives as inhibitors of Hepatitis A Virus (HAV) 3C proteinase

Hepatitis A virus (HAV) 3C proteinase is a picornaviral cysteine proteinase that is essential for cleavage of the initially synthesized viral polyprotein precursor to mature fragments and is therefore required for viral replication in vivo. Since the enzy

Reduction of 2-acylaziridines by samarium(II) iodide. An efficient and regioselective route to β-amino carbonyl compounds

A convenient method for the reduction of 2-acylaziridines, aziridine-2- carboxylates and aziridine-2-carboxamides is described. The reduction of all of the substrates examined was extremely rapid and highly regioselective, giving rise to β-amino carbonyl compounds. This method appears to be general for all of the classes of aziridines mentioned above, and also tolerates a variety of nitrogen protecting groups.