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193891-16-6

4-chloro-7-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 193891-16-6 Structure

  • Basic information

    1. Product Name: 4-chloro-7-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine
    2. Synonyms:
    3. CAS NO:193891-16-6
    4. Molecular Formula:
    5. Molecular Weight: 534.999
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 193891-16-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-chloro-7-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-chloro-7-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine(193891-16-6)
    11. EPA Substance Registry System: 4-chloro-7-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine(193891-16-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 193891-16-6(Hazardous Substances Data)

193891-16-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 193891-16-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,3,8,9 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 193891-16:
(8*1)+(7*9)+(6*3)+(5*8)+(4*9)+(3*1)+(2*1)+(1*6)=176
176 % 10 = 6
So 193891-16-6 is a valid CAS Registry Number.

193891-16-6Relevant articles and documents

Methylated DNA: The influence of 7-deaza-7-methylguanine on the structure and stability of oligonucleotides

Seela,Chen

, p. 1073 - 1086 (1997)

The 7-deaza-2'-deoxy-7-methylguanosine (2b) [9], which is the glycosylic-bond-stable, noncharged analogue of 2'-deoxy-7-methylguanosine (1b), was incorporated in DNA by solid-phase synthesis. As building blocks, the protected phosphonate 3a and the phosphoramidite 3b were prepared. The 7- methyl group of 2b stabilizes the B-DNA duplex compared to 7-deaza-2'- deoxyguanosine but does not induce a B-Z transition as it is known from compound 1b. The stabilization by the 7-deaza-7-methylguanine moiety is sequence-dependent, and the nearest-neighbor influence is different from that of 7-deazaguanine. Homooligonucleotides of 2b show sigmoidal melting indicating a highly ordered single-stranded structure. In general, oligonucleotides containing 2b are very stable against hydrolysis with calf- spleen phosphodiesterase (CS-PDE, 5' 3' exonuclease), while phosphodiester hydrolysis with snake-venom phosphodiesterase (SV-PDE, 3'- 5'exonuclease) is only slightly reduced.

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