193952-10-2Relevant academic research and scientific papers
Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway
Ma, Yingying,Yang, Xiaorong,Han, Hongwei,Wen, Zhongling,Yang, Minkai,Zhang, Yahan,Fu, Jiangyan,Wang, Xuan,Yin, Tongming,Lu, Guihua,Qi, Jinliang,Lin, Hongyan,Wang, Xiaoming,Yang, Yonghua
, (2021/04/12)
Triple-negative breast cancer (TNBC) has an unfavorable prognosis attribute to its low differentiation, rapid proliferation and high distant metastasis rate. PI3K/Akt/mTOR as an intracellular signaling pathway plays a key role in the cell proliferation, m
N-Aryl Amides as Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Contrast Agents
Cai, Xuekang,Zhang, Jia,Lu, Jiaqi,Yi, Long,Han, Zheng,Zhang, Shuixing,Yang, Xing,Liu, Guanshu
supporting information, p. 11705 - 11709 (2020/08/13)
Chemical exchange saturation transfer (CEST) MRI has recently emerged as a versatile molecular imaging approach in which diamagnetic compounds can be utilized to generate an MRI signal. To expand the scope of CEST MRI applications, herein, we systematical
SMALL MOLECULES AS EPIGENETIC MODULATORS OF LYSINE-SPECIFIC DEMETHYLASE 1 AND METHODS OF TREATING DISORDERS
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Page/Page column 49, (2012/03/27)
The invention provides for novel compounds which are inhibitors of lysine- specific demethylase 1 (LSDl). Such compounds may be used to treat disorders, including cancer.
