193954-28-8

Basic information

• Product Name: Fmoc-L-beta-homophenylalanine
• Synonyms: Fmoc-b-HoPhe-OH;(S)-3-(Fmoc-amino)-4-phenylbutyric acid, Fmoc-L-β-homophenylalanine;N-FMoc-L-^b-hoMophenylalanine, 95%;Fmoc-L-BETA-Homo-Phe-OH;(S)-3-(Fmoc-amino)-4-phenylbutanoic acid;(S)-Fmoc-3-amino-4-phenylbutyric acid;Fmoc-L-β-homophenylalanine≥ 99% (HPLC, Chiral purity);N-Fmoc-L-beta-homophenylalanine
• CAS NO: 193954-28-8
• Molecular Formula: C₂₅H₂₃NO₄
• Molecular Weight: 401.45
• Product Categories: β-Homo Amino Acids;Beta amino acids
• Mol File: 193954-28-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 110-112 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
• Boiling Point: 633.217 °C at 760 mmHg
• Flash Point: 336.758 °C
• Appearance: /
• Density: 1.255 g/cm³
• Vapor Pressure: 6.64E-17mmHg at 25°C
• Refractive Index: 1.624
• Storage Temp.: 2-8°C
• PKA: 4.38±0.10(Predicted)
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: Fmoc-L-beta-homophenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: Fmoc-L-beta-homophenylalanine(193954-28-8)
• EPA Substance Registry System: Fmoc-L-beta-homophenylalanine(193954-28-8)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 193954-28-8(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

N-Fmoc-L-beta-homophenylalanine is used for producing high quality peptides.

InChI:InChI=1/C25H23NO4/c27-24(28)15-18(14-17-8-2-1-3-9-17)26-25(29)30-16-23-21-12-6-4-10-19(21)20-11-5-7-13-22(20)23/h1-13,18,23H,14-16H2,(H,26,29)(H,27,28)/t18-/m1/s1

Upstream product

• 103321-57-9 2S-flouren-9-ylmethoxycarbonylamino-3-phenylpropionyl chloride 
• 35661-40-6 N-Fmoc L-Phe 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 114645-20-4 (S)-3-amino-4-phenylbutanoic acid trifluoroacetate 
• 172097-41-5 (S)-1-diazo-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-phenylbutan-2-one 

Downstream Products

• 270062-99-2 (S)-3-carboxymethyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid 9H-fluoren-9-ylmethyl ester 

Relevant articles and documents

Solid-phase synthesis of a β-dodecapeptide with seven functionalized side chains and CD-spectroscopic evidence for a dramatic structural switch when going from water to methanol solution

An all-β3-dodecapeptide with a protected N-terminal thiol-anchoring group and with seven side chains has been synthesized in multi-mg amounts by the manual solid-phase technique, applying Fmoc methodology and the Wang resin. The sequence is β-H

Conformationally homogeneous cyclic tetrapeptides: Useful new three-dimensional scaffolds

The most commonly recognized motifs in protein-protein interactions are γ and β turns, which are defined by three to four contiguous amino acids in a peptide sequence. Cyclic tetrapeptides thus represent minimalist turn mimetics, but their usefulness is c

Synthesis of β-amino acids: 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyl-uronium tetrafluoroborate (TBTU) for activation of Fmoc-/Boc-/Z-α-amino acids

A new and efficient method for the homologation of urethane protected α-amino acids to its β-homomers by the Arndt-Eistert method using TBTU as a coupling agent is described. Several Fmoc-/Boc-/Z-protected α-amino diazoketone derivatives have been obtaine