270062-99-2 Usage
Uses
Used in Organic Chemistry:
Fmoc-(S)-2-tetrahydroisoquinoline acetic acid is used as a protecting group in organic chemistry for the synthesis of peptides and small molecules. Its application is crucial for protecting the amine group during chemical reactions, ensuring that the molecule's integrity is maintained until the Fmoc group is selectively removed under mild conditions.
Used in Solid-Phase Peptide Synthesis:
In the pharmaceutical and biotechnological industry, Fmoc-(S)-2-tetrahydroisoquinoline acetic acid is utilized as a key component in solid-phase peptide synthesis. Its stability and selective deprotection properties allow for the efficient and controlled synthesis of peptides, which are essential for drug development and other therapeutic applications.
Used in Combinatorial Chemistry:
Fmoc-(S)-2-tetrahydroisoquinoline acetic acid is also employed in combinatorial chemistry, a technique used to discover new compounds and optimize their properties. Its selective deprotection feature enables the synthesis of diverse compound libraries, facilitating the identification of potential drug candidates and other bioactive molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 270062-99-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,0,0,6 and 2 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 270062-99:
(8*2)+(7*7)+(6*0)+(5*0)+(4*6)+(3*2)+(2*9)+(1*9)=122
122 % 10 = 2
So 270062-99-2 is a valid CAS Registry Number.
InChI:InChI=1/C26H23NO4/c28-25(29)14-19-13-17-7-1-2-8-18(17)15-27(19)26(30)31-16-24-22-11-5-3-9-20(22)21-10-4-6-12-23(21)24/h1-12,19,24H,13-16H2,(H,28,29)/t19-/m0/s1
270062-99-2Relevant academic research and scientific papers
Facile synthesis of Fmoc-N-methylated α- and β-amino acids
Govender, Thavendran,Arvidsson, Per I.
, p. 1691 - 1694 (2007/10/03)
A highly efficient and environmentally friendly synthesis of Fmoc-N-methyl α- and β-amino acids from the corresponding Fmoc-amino acid, via intermediate oxazolidinones/oxazinanones, has been developed. Microwave heating for 3 min was required for the synt
