193965-30-9

Basic information

• Product Name: 5-METHOXYBENZO[B]THIOPHENE-2-BORONIC ACID
• Synonyms: 5-METHOXYBENZO[B]THIOPHENE-2-BORONIC ACID;5-methoxybenzo[b]thiophen-2-ylboronic acid
• CAS NO: 193965-30-9
• Molecular Formula: C₉H₉BO₃S
• Molecular Weight: 208.05
• Mol File: 193965-30-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 423.1 °C at 760 mmHg
• Flash Point: 209.7 °C
• Appearance: /
• Density: 1.35 g/cm³
• Vapor Pressure: 6.51E-08mmHg at 25°C
• Refractive Index: 1.64
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-METHOXYBENZO[B]THIOPHENE-2-BORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHOXYBENZO[B]THIOPHENE-2-BORONIC ACID(193965-30-9)
• EPA Substance Registry System: 5-METHOXYBENZO[B]THIOPHENE-2-BORONIC ACID(193965-30-9)

Safety Data

• Hazardous Substances Data: 193965-30-9(Hazardous Substances Data)

Usage

Uses

5-Methoxybenzo[b]thiophene-2-boronic acid acts as a reagent in the synthesis of dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors in relation to structure-activity studies on conformationally restricted C3-side chain.

InChI:InChI=1/C9H9BO3S/c1-13-7-2-3-8-6(4-7)5-9(14-8)10(11)12/h2-5,11-12H,1H3

Upstream product

• 20532-30-3 5-methoxybenzothiophene 

Downstream Products

• 193965-31-0 5-methoxy-2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophene 
• 1097778-18-1 ethyl 3-(5-methyloxy-1-benzothien-2-yl)benzoate 
• 1097776-88-9 ethyl 4-(5-methyloxy-1-benzothien-2-yl)benzoate 
• 193965-32-1 4-Fluorophenyl 5-Methoxy-2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl Ketone 

Relevant articles and documents

C-benzo five-membered heteroaromatic aryl glucoside derivative as well as preparation method and application thereof

The invention discloses a C-benzo five-membered heteroaromatic aryl glucoside derivative shown in the general formula (I) (in the description), a preparation method of the derivative or an intermediate of the derivative, as well as application of the derivative. In the general formula (I), R, R1, R2, R3, R4, X and Y are defined in the description. The C-benzo five-membered heteroaromatic aryl glucoside derivative is novel in structure, has quite strong inhibitory activity on SGLT-2, has high selection ratio for SGLT-1 and SGLT-2, and can be used for preparing drugs for treating and preventing diseases relevant to SGLT-2.

Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

The compounds of the present invention are represented by the chemical structure found in Formula (I): wherein: the carbon atom designated * is in the R or S configuration; and X is a fused bicyclic carbocycle or heterocycle selected from the group consisting of benzofuranyl, benzo[b]thiophenyl, benzoisothiazolyl, benzoisoxazolyl, indazolyl, indolyl, isoindolyl, indolizinyl, benzoimidazolyl, benzooxazolyl, benzothiazolyl, benzotriazolyl, imidazo[1,2-a]pyridinyl, pyrazolo[1,5-a]pyridinyl, [1,2,4]triazolo[4,3-a]pyridinyl, thieno[2,3-b]pyridinyl, thieno[3,2-b]pyridinyl, 1H-pyrrolo[2,3-b]pyridinyl, indenyl, indanyl, dihydrobenzocycloheptenyl, tetrahydrobenzocycloheptenyl, dihydrobenzothiophenyl, dihydrobenzofuranyl, indolinyl, naphthyl, tetrahydronaphthyl, quinolinyl, isoquinolinyl, 4H-quinolizinyl, 9aH-quinolizinyl, quinazolinyl, cinnolinyl, phthalazinyl, quinoxalinyl, benzo[1,2,3]triazinyl, benzo[1,2,4]triazinyl, 2H-chromenyl, 4H-chromenyl, and a fused bicyclic carbocycle or fused bicyclic heterocycle optionally substituted with substituents (1 to 4 in number) as defined in R14; with R1, R2, R3, R4, R5, R6, R7, R8, and R14 defined herein.