193967-43-0

Basic information

• Product Name: C₆₇H₇₁N₁₀O₁₄PSi
• Synonyms: C₆₇H₇₁N₁₀O₁₄PSi
• CAS NO: 193967-43-0
• Molecular Weight: 1299.42
• Mol File: 193967-43-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₆₇H₇₁N₁₀O₁₄PSi(CAS DataBase Reference)
• NIST Chemistry Reference: C₆₇H₇₁N₁₀O₁₄PSi(193967-43-0)
• EPA Substance Registry System: C₆₇H₇₁N₁₀O₁₄PSi(193967-43-0)

Safety Data

• Hazardous Substances Data: 193967-43-0(Hazardous Substances Data)

Upstream product

• 1904-78-5 2-nitrobenzylamine 
• 193967-39-4 C₆₀H₆₅N₈O₁₂PSi 
• 552-89-6 2-nitro-benzaldehyde 
• 135436-97-4 2-nitrobenzaldehyde-(O-methyl oxime) 

Downstream Products

• 193967-44-1 (2-Nitro-benzyl)-phosphoramidic acid (2R,3S,5S)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester (2R,3S,5S)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 

Relevant articles and documents

A new route to oligodeoxynucleoside phosphoramidates (P-NH2)

We describe a new strategy to introduce phosphoramidate (P-NH2) internucleosidic linkages in oligonucleoside phosphodiesters using dimer building blocks. The P-NH2 function is generated under photolysis of the N-2-nitrobenzylphosphoramidate linkage (P-NHR). We achieved the synthesis of N-2-nitrobenzylphosphoramidate β and α-anomeric nucleotides dimers via either phosphoramidite or H-phosphonate chemistry, α-dimer (P-NHR) was incorporated at defined positions into α-oligonucleoside phosphodiesters and the P-NH2 linkage was liberated by U.V irradiation.