135436-97-4

Basic information

• Product Name: 2-Nitrobenzaldehyde o-methyloxime
• Synonyms: 2-Nitrobenzaldehyde o-methyloxime
• CAS NO: 135436-97-4
• Molecular Formula: C₈H₈N₂O₃
• Molecular Weight: 180.16
• Mol File: 135436-97-4.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Nitrobenzaldehyde o-methyloxime(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Nitrobenzaldehyde o-methyloxime(135436-97-4)
• EPA Substance Registry System: 2-Nitrobenzaldehyde o-methyloxime(135436-97-4)

Safety Data

• Hazardous Substances Data: 135436-97-4(Hazardous Substances Data)

Upstream product

• 1392207-68-9 C₈H₈⁽²⁾HNO 
• 100-52-7 benzaldehyde 
• 10229-53-5 (E)-benzaldehyde O-methyloxime 
• 186581-53-3 diazomethane 
• 4836-00-4 (E)-2-nitrobenzaldehyde oxime 
• 74-88-4 methyl iodide 
• 60-29-7 diethyl ether 
• 593-56-6 N-methoxylamine hydrochloride 
• 552-89-6 2-nitro-benzaldehyde 
• 71-43-2 benzene 
• 124-41-4 sodium methylate 
• 77-78-1 dimethyl sulfate 
• 67-56-1 methanol 
• 6635-41-2 (Z)-2-nitrobenzaldehyde oxime 

Downstream Products

• 552-89-6 2-nitro-benzaldehyde 
• 4836-00-4 (E)-2-nitrobenzaldehyde oxime 
• 593-56-6 N-methoxylamine hydrochloride 
• 6476-32-0 o-phenoxybenzonitrile 
• 305811-22-7 2-aminobenzaldehyde-(O-methyl oxime) 
• 1208259-15-7 2-(4-methylphenyl)-quinazoline 
• 1222094-28-1 2-(4-bromo-phenyl)-quinazoline 
• 1208259-07-7 2-(4-fluorophenyl)-quinazoline 
• 67205-04-3 2-(4-methoxyphenyl)quinazoline 
• 25855-20-3 2-phenylquinazoline 
• 1208259-19-1 2-(m-tolyl)-3,4-dihydroquinazoline 
• 193967-35-0 C₆₇H₇₁N₁₀O₁₄PSi 
• 193967-43-0 C₆₇H₇₁N₁₀O₁₄PSi 
• 193967-36-1 (2-Nitro-benzyl)-phosphoramidic acid (2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 

Relevant articles and documents

Preparation method O - alkyl substituted hydroxylamine salt

The invention relates to a preparation method of N - alkyl substituted hydroxylamine salt, and belongs to fine chemical engineering. Pesticide or bulk pharmaceutical chemicals technical field. The present invention reacts with the N - alkyl of the oxime with an inorganic salt of hydroxylamine to give N - alkyl-substituted hydroxylamine salt and oxime. The invention provides an efficient and environment-friendly method for preparing N - alkyl substituted hydroxylamine salt, and simultaneously, an N - alkyl substituted hydroxylamine salt is prepared, and the oxime can be re-prepared to form N - alkylate of oxime so as to realize the material circulation. No equivalent acid is used in the reaction process. Alkali neutralization, avoided the current method to use a large amount of acid, alkali and produce inorganic salt solid waste shortcoming, environmental protection more. The preparation method is mild in reaction condition, and the defects of high pollution and high energy consumption of the traditional process are overcome. In-flight R1 , R2 What is R is as claimed in the claims and the description.

A O-nitrobenzaldehyde synthetic method of compound

The invention provides a preparation method for an o-nitrobenzaldehyde compound. The method directly taking benzaldehyde compounds as starting raw materials comprises the following steps: firstly, converting a formyl group into an O-methyl oximido; secondly, taking divalent palladium salt as a catalyst, and realizing the carbon-hydrogen bond activation single nitration reaction on an o-position of an oximido under the condition that both an oxidant and a nitration agent exist; finally, removing the O-methyl oximido by using strong organic acid to obtain the o-nitrobenzaldehyde compound. The nitration method provided by the invention has the advantage of specificity in the o-position of a nitration position, the reaction process is safe and environment-friendly, the substrate is excellent in adaptability, and various substituents can realize o-position nitration; various benzaldehyde is directly taken as raw materials, so that the reaction steps are simple, and the synthesizing method is a novel route for synthesizing various o-nitrobenzaldehyde compounds containing substituents.

Regiospecific synthesis of substituted 2-nitrobenzaldehydes from benzaldehydes through palladium-catalyzed chelation-assisted C-H nitration

A regiospecific synthesis of substituted 2-nitrobenzaldehydes from substituted benzaldehydes has been developed that involves a three-step process with palladium-catalyzed chelation-assisted C-H nitration as the key step. In the process, O-methyl aldoxime serves as a removable directing group for the palladium-catalyzed ortho-nitration of substituted benzaldoximes and it can be removed in subsequent conversion of the resulting 2-nitrobenzaldoximes into 2-nitrobenzaldehydes.