193980-00-6

Upstream product

• 51608-60-7 N-(benzylidene)-p-methylbenzenesulfonamide 
• 155095-23-1 2-propanoyl-3-phenyl-l-menthopyrazole 
• 181874-04-4 trans-(2R,3S)-(+)-N-(p-toluenesulfonyl)-2-methyl-2-carbomethoxy-3-phenylaziridine 
• 181874-01-1 trans-(S_S,2R,3S)-(+)-N-(p-toluenesulfinyl)-2-methyl-2-carbomethoxy-3-phenylaziridine 
• 350479-90-2 (S,E)-N-benzylidene-4-methylbenzenesulfinamide 
• 100-52-7 benzaldehyde 
• 943241-35-8 (S)-(+)-N-(benzylidene)-2,4,6-triisopropylbenzenesulfinamide 
• 943241-44-9 (2R,3R)-(-)-3-amino-N-methoxy-N,2-dimethyl-3-phenylpropanamide 
• 943241-41-6 (S_S,2R,3R)-(+)-N-methoxy-N,2-dimethyl-3-(2,4,6-triisopropylphenylsulfinylamino)-3-phenylpropanamide 
• 943241-46-1 (2R,3R)-(+)-N-methoxy-N,2-dimethyl-3-(p-toluenesulfonamido)-3-phenylpropanamide 
• 127598-01-0 (1R,2R)-N-(3-hydroxy-2-methyl-1-phenyl-propyl)-4-methyl-benzenesulfonamide 
• 165036-40-8 (4S,5R)-4-methyl-3-<(2R,3R)-2-methyl-3-phenyl-3-(tosylamino)propionyl>-5-phenyloxazolidin-2-one 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 155156-03-9 (3R,4R)-3-methyl-4-phenylazetidin-2-one 
• 165036-42-0 (3R,4R)-3-methyl-4-phenyl-1-tosylazetidin-2-one 

Relevant academic research and scientific papers

Asymmetric synthesis of syn-α-substituted β-amino ketones by using sulfinimines and prochiral weinreb amide enolates

syn-α-Substituted β-amino Weinreb amides are new chiral building blocks for asymmetric synthesis of syn-α-substituted β-amino acids, aldehydes, and ketones and are prepared by addition of prochiral lithium enolates of Weinreb amides to sulfinimines (N-sul

Aziridine 2-carboxylate ester mediated asymmetric synthesis of α-alkyl β-amino acids

The highly stereoselective ring opening of N-tosylaziridine 2-carboxylate esters with LiAIH4 followed by oxidation of the ensuing syn alcohols results in a highly efficient 4 step asymmetric synthesis of α-methyl β-amino acids from N-sulfinylaziridine 2-carboxylate esters.

Synthesis of Optically Active β-Lactams by the Reaction of 2-Acyl-3-phenyl-l-menthopyrazoles with C=N Compounds

The reaction of 1-acyl-3,5-dimethyIpyrazoles 1 with C=N compounds was kinetically controlled with syn stereoselectivity through a lithium enolate intermediate using lithium diisopropylamide. In contrast, the anti stereoselective reaction of 1 was caused b

Addition to activated imines of enolates from chiral N-acyloxazolidinones

The lithium and titanium enolates of N-acyloxazolidinones 1a-c add in their chelated forms to PhCH=NTs, to give stereoselectively the β-amino acid derivatives 3a-c and 4a-c. The relative configurations of the newly created chiral centres were established