194039-57-1

Basic information

• Product Name: D-Alanine, D-alanyl-L-lysyl-3-cyclohexyl-L-alanyl-L-valyl-L-alanyl-L-alanyl-L-tryptophyl-L- threonyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl-
• CAS NO: 194039-57-1
• Molecular Formula: C65H108N16O15
• Molecular Weight: 1353.67
• Mol File: 194039-57-1.mol

Chemical Properties

• CAS DataBase Reference: D-Alanine, D-alanyl-L-lysyl-3-cyclohexyl-L-alanyl-L-valyl-L-alanyl-L-alanyl-L-tryptophyl-L- threonyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl-(CAS DataBase Reference)
• NIST Chemistry Reference: D-Alanine, D-alanyl-L-lysyl-3-cyclohexyl-L-alanyl-L-valyl-L-alanyl-L-alanyl-L-tryptophyl-L- threonyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl-(194039-57-1)
• EPA Substance Registry System: D-Alanine, D-alanyl-L-lysyl-3-cyclohexyl-L-alanyl-L-valyl-L-alanyl-L-alanyl-L-tryptophyl-L- threonyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl-(194039-57-1)

Safety Data

• Hazardous Substances Data: 194039-57-1(Hazardous Substances Data)

Upstream product

• 68858-20-8 Fmoc-Val-OH 
• 35661-60-0 Fmoc-Leu-OH 
• 35661-39-3 N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine 
• 71989-26-9 Fmoc-Lys(tert-butoxycarbonyl) 
• 71989-35-0 Fmoc-Thr(tBu)-OH 
• 35661-38-2 N-(9-fluorenylmethoxycarbonyl)-D-alanine 
• 143824-78-6 3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Synthesis of a trimeric gp120 epitope mimic conjugated to a T-helper peptide to improve antigenicity

A fully synthetic trivalent mimotope of gp120 conjugated to pan allelic HLA DR binding epitope was prepared using solid-phase peptide synthesis and optimized copper-catalyzed azide-alkyne cycloaddition. The methodology efficiently provides chemically uniform heteromultimeric peptide constructs with enhanced binding, avidity, and specificity toward an established HIV-neutralizing human antibody, MAb b12. The versatile synthetic strategy serves as a powerful platform for the development of synthetic peptides as potential HIV-1 vaccine candidates.