1941-24-8

Usage

Uses

Used in Pharmaceutical Industry:
Tetramethylammonium nitrate is used as a glycolate oxidase inhibitor for its ability to inhibit the enzyme glycolate oxidase, which plays a crucial role in certain metabolic pathways. This inhibition can be beneficial in the development of drugs targeting specific conditions or diseases.
Used in Chemical Synthesis:
Tetramethylammonium nitrate, due to its unique chemical structure, can be utilized as an intermediate or reagent in the synthesis of various organic compounds, contributing to the advancement of chemical research and development.
Used in Research and Development:
In the field of research and development, Tetramethylammonium nitrate can be employed as a tool to study the effects of glycolate oxidase inhibition on cellular processes and to develop new methodologies for enzyme inhibition studies.
Used in Agricultural Industry:
Tetramethylammonium nitrate may also find applications in the agricultural industry, where it could be used to control or manage specific enzymatic processes in plants, potentially leading to improved crop yields or resistance to certain diseases.

Purification Methods

Recrystallise the nitrate from EtOH and dry at 110o in an air oven. [Coats & Taylor J Chem Soc 1498 1936, Beilstein 4 III 113, 4 IV 147.]

InChI:InChI=1/C4H12N.NO3/c1-5(2,3)4;2-1(3)4/h1-4H3;/q+1;-1

Upstream product

• 60-29-7 diethyl ether 
• 64-19-7 acetic acid 
• 999-77-9 tetramethylammonium azide 
• 13444-90-1 Nitryl chloride 
• 75-59-2 tetramethyl ammoniumhydroxide 
• 64-20-0 tetramethylammonium bromide 
• 616-38-6 carbonic acid dimethyl ester 
• 15625-60-2 tetramethyl-ammonium; tetrachloro iodide 
• 1838-41-1 tetramethylammonium dichloroiodate(I) 
• 64-17-5 ethanol 

Relevant academic research and scientific papers

Tetraalkylammonium Salts of Platinum Nitrato Complexes: Isolation, Structure, and Relevance to the Preparation of PtOx/CeO2 Catalysts for Lowerature CO Oxidation

A series of tetraalkylammonium salts with anionic platinum nitrato complexes (Me4N)2[Pt2(μ-OH)2(NO3)8] (1), (Et4N)2[Pt2(μ-OH)2(NO3)8] (2), (n-Pr4N)2[Pt2(μ-OH)2(NO3)8] (3b), (n-Pr4N)2[Pt(NO3)6] (3a), and (n-Bu4N)2[Pt(NO3)6] (4) were isolated from nitric acid solutions of [Pt(H2O)2(OH)4] in high yield. The structures of salts 2, 3a, 3b, and 4, prepared for the first time, were characterized by X-ray diffraction. The sorption of [Pt(NO3)6]2- and [Pt2(μ-OH)2(NO3)8]2- complexes onto the ceria surface from acetone solutions of salts 4 and 1 was examined. The dimeric anion was shown to quickly and irreversibly chemisorb onto the CeO2 carrier, selectively transforming into Pt(II) centers after thermal treatment, becoming active in the lowerature CO oxidation reaction (T50% = 110 °C at a space velocity of 240 000 h-1). By contrast, the homoleptic complex [Pt(NO3)6]2- did not interact with the ceria, which may be attributed to the substitutional inertness of the [Pt(NO3)6]2- anion. We believe that the strategy based on the sorption of polynuclear platinum nitrato complexes is an effective route to prepare ionic platinum species uniformly distributed on an oxide carrier for various catalytic applications.

A calorimetric study of the hydrolysis and peroxide complex formation of the uranyl(vi) ion

The enthalpies of reaction for the formation of uranyl(vi) hydroxide {[(UO2)2(OH)2]2+, [(UO 2)3(OH)4]2+, [(UO2) 3(OH)5]+, [(UO2)3(OH) 6](aq), [(UO2)3(OH) 7]-, [(UO2)3(OH)8] 2-, [(UO2)(OH)3]-, [(UO 2)(OH)4]2-} and peroxide complexes {[UO 2(O2)(OH)]- and [(UO2) 2(O2)2(OH)]-} have been determined from calorimetric titrations at 25 °C in a 0.100 M tetramethyl ammonium nitrate ionic medium. The hydroxide data have been used to test the consistency of the extensive thermodynamic database published by the Nuclear Energy Agency (I. Grenthe, J. Fuger, R. J. M. Konings, R. J. Lemire, A. B. Mueller, C. Nguyen-Trung and H. Wanner, Chemical Thermodynamics of Uranium, North-Holland, Amsterdam, 1992 and R. Guillaumont, T. Fanghaenel, J. Fuger, I. Grenthe, V. Neck, D. J. Palmer and M. R. Rand, Update on the Chemical Thermodynamics of Uranium, Neptunium, Plutonium, Americium and Technetium, Elsevier, Amsterdam, 2003). A brief discussion is given about a possible structural relationship between the trinuclear complexes [(UO2)3(OH) n]6-n, n = 4-8.

Alkylation of ammonium salts catalyzed by imidazolium-based ionic liquid catalysts

Quaternary ammonium salts were synthesized from ammonium salts and dialkyl carbonates over imidazolium ionic liquid catalysts. The reaction gave almost stoichiometric amounts of the quaternary ammonium salts for halides and nitrates. It was found that the electron-donating property of the alkyl moieties of ammonium cations, the electrophilic nature of the alkyl group of the carbonate, the acidity of the acid that the anion of the ammonium salt corresponds to, and the steric hindrance of the ammonium salts and the dialkyl carbonates are the key factors that influence the yields of quaternary ammonium salts. Strong electron-donating alkyl groups on the nitrogen atom of the ammonium salt, electron-withdrawing groups on the methylene carbon of dialkyl carbonate, and weaker steric hindrance of the starting ammonium salts and dialkyl carbonates favor the alkylation reaction of ammonium salts.

The synthesis of quaternary ammonium salts from ammonium salts and dialkyl carbonate

Quaternary ammonium salts were synthesized from ammonium salts and dialkyl carbonates over an ionic liquid catalyst 1-ethyl-3-methylimidazolium bromide. The Royal Society of Chemistry 2006.

Thermochemistry of Polyhalides. Part 5. Standard Enthalpies of Formation of Tetramethylammonium and Tetraethylammonium Tetrachloroiodates

The standard enthalpies of formation of methyl- and ethyl-ammonium tetrachloroiodates NRnH4-nICl4 (R = Me or Et, 0 /= n /= 4), have been determined by a solution reaction method using aqueous silver nitrate.Lattice energies have been estimated from these data and trends in these and in the standard enthalpies of formation as a function of alkyl substitution are discussed.