19411-80-4

Basic information

• Product Name: Butanoic acid, 2-[(4-chlorophenyl)methylene]-3-oxo-, ethyl ester
• CAS NO: 19411-80-4
• Molecular Formula: C13H13ClO3
• Molecular Weight: 252.697
• Mol File: 19411-80-4.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 2-[(4-chlorophenyl)methylene]-3-oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-[(4-chlorophenyl)methylene]-3-oxo-, ethyl ester(19411-80-4)
• EPA Substance Registry System: Butanoic acid, 2-[(4-chlorophenyl)methylene]-3-oxo-, ethyl ester(19411-80-4)

Safety Data

• Hazardous Substances Data: 19411-80-4(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 72796-79-3 2-[(4-Chloro-phenyl)-pyrazol-1-yl-methyl]-3-oxo-butyric acid ethyl ester 
• 1026720-79-5 2-Acetyl-3-(4-chloro-phenyl)-4-methyl-4-nitro-pentanoic acid ethyl ester 
• 184945-33-3 6-carbamoylmethylsulfanyl-4-(4-chloro-phenyl)-5-cyano-2-methyl-1,4-dihydro-pyridine-3-carboxylic acid ethyl ester 
• 108262-55-1 Ethyl 3-(p-Chlorophenyl)-5-methyl-N-(p-methylbenzylidene)-2-aminofuran-4-carboxylate 
• 35271-74-0 3-(4-chlorophenyl)pentane-1,5-dioic acid 
• 1134-47-0 4-amino-3-(4-chlorophenyl)butanoic acid 
• 1141-23-7 3-(p-chlorophenyl)glutaramic acid 
• 84803-46-3 4-(4-chlorophenyl)piperidine-2,6-dione 
• 105412-34-8 ethyl methyl 4-(4-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 1449242-16-3 ethyl 2-amino-4-(4-chlorophenyl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate 
• 1449242-51-6 ethyl 4-(4-chlorophenyl)-6-methyl-2-(8-methyl-[1,3]dioxolo[4,5-g]quinazolin-6-ylamino)-1,4-dihydropyrimidine-5-carboxylate 

Relevant articles and documents

Cross-linked polystyrene-TiCl4 complex as a reusable Lewis acid catalyst for solvent-free Knoevenagel condensations of 1,3-dicarbonyl compounds with aldehydes

Cross-linked polystyrene copolymer beads with the average particle size in the range of (50–80 mesh size) were prepared by a new method, characterized and functionalized with titanium tetrachloride to afford the corresponding polystyrene?titanium tetrachloride complex in one step reaction and characterized by FT-IR, UV, TGA, DSC, XRD, SEM, BET. This polymer metal complex (PS/TiCl4) was used as a heterogeneous, recoverable, reusable Lewis acid for solvent-free Knoevenagel condensations of 1,3-diketones with aromatic aldehydes under green and mild conditions. The rate of reactions was found to decrease with an increasing percentage of crosslinking and the mesh size of the copolymer beads. This complex showed good stability and catalytic activity in the Knoevenagel reactions.

Facile construction of 4H-chromenes via Michael addition of phenols to benzylidene oxobutanoates and their successful conversion into pyranocoumarins

An efficient and simple approach for the synthesis of functionalized 4H-chromenes has been developed via acid catalyzed Michael addition of phenols to benzylidene oxobutanoates. Preliminary mechanistic studies were conducted, suggesting that intermediate

Visible-light-promoted iminyl-radical formation from Acyl oximes: A unified approach to pyridines, quinolines, and phenanthridines

A unified strategy involving visible-light-induced iminyl-radical formation has been established for the construction of pyridines, quinolines, and phenanthridines from acyl oximes. With fac-[Ir(ppy)3] as a photoredox catalyst, the acyl oximes were converted by 1 e- reduction into iminyl radical intermediates, which then underwent intramolecular homolytic aromatic substitution (HAS) to give the N-containing arenes. These reactions proceeded with a broad range of substrates at room temperature in high yield. This strategy of visible-light-induced iminyl-radical formation was successfully applied to a five-step concise synthesis of benzo[c]phenanthridine alkaloids.