194161-13-2 Usage
Uses
Used in Cancer Therapy:
(1R)-1-(2,6-difluorophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole is used as a therapeutic agent for the treatment of various types of cancers, including breast, ovarian, and prostate cancers. Its ability to inhibit PARP makes it a promising candidate for use in combination with chemotherapy and radiation to enhance the effectiveness of cancer treatments.
Used in Inflammatory and Autoimmune Disease Treatment:
(1R)-1-(2,6-difluorophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole is also being studied for its potential in the treatment of inflammatory and autoimmune diseases. Its exact role and mechanism in these conditions are still under investigation, but its potential as a therapeutic agent is being explored in ongoing research and clinical trials.
Further research and clinical trials are ongoing to explore the full potential of (1R)-1-(2,6-difluorophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole in the field of medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 194161-13-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,1,6 and 1 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 194161-13:
(8*1)+(7*9)+(6*4)+(5*1)+(4*6)+(3*1)+(2*1)+(1*3)=132
132 % 10 = 2
So 194161-13-2 is a valid CAS Registry Number.
194161-13-2Relevant academic research and scientific papers
One-pot synthesis of 1-aryl-1 H,3 H-thiazolo[3,4-a[benzimidazoles using magnetite-linked sulfonic acid as catalyst
Wu, Liqiang,Wang, Xiao
, p. 1851 - 1857 (2015/10/29)
A series of 1-aryl-1H,3H-thiazolo[3,4-a]benzimidazole derivatives have been synthesized via the three-component reaction of o-phenylenediamine, aromatic aldehydes, and 2-mercaptoacetic acid, catalyzed by magnetite-linked sulfonic acid. This method has the
An ionic liquid mediated one-pot synthesis of substituted thiazolidinones and benzimidazoles
Yadav, Ashok K.,Kumar, Manoj,Yadav, Tripti,Jain, Renuka
scheme or table, p. 5031 - 5034 (2009/12/01)
An expeditious one-pot synthesis of 2,3-diaryl/2-aryl-3-heteroaryl-1,3-thiazolidin-4-ones and 1-aryl-1H,3H-thiazolo[3,4-a]benzimidazoles have been accomplished by condensing hetero/aromatic amine, 2-mercaptoacetic acid, aromatic aldehyde and 1,2-phenylenediamine, 2-mercaptoacetic acid and aromatic aldehyde, respectively, in ionic liquids, viz, 1-butyl-3-methyl-imidazolium tetrafluoroborate and 1-methoxyethyl-3-methylimidazolium trifluoroacetate.
