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methyl N2-(tert-butoxycarbonyl)-N5-phenyl-L-glutaminate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

194206-03-6

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194206-03-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 194206-03-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,2,0 and 6 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 194206-03:
(8*1)+(7*9)+(6*4)+(5*2)+(4*0)+(3*6)+(2*0)+(1*3)=126
126 % 10 = 6
So 194206-03-6 is a valid CAS Registry Number.

194206-03-6Relevant articles and documents

Synthesis of l -Kynurenine and Homo- l -Kynurenine via an Aza-Fries Rearrangement

Bonilla-Reyes, Edgar,Sánchez-Carrillo, Adrian,Vázquez, Alfredo

, p. 3473 - 3479 (2020)

l -Kynurenine, a non-proteinogenic amino acid, is the primary metabolite of tryptophan via the kynurenine pathway. Kynurenine is involved in a variety of biological processes occurring in the human body, notably in the central nervous system. Thus, the st

PEPTIDOMIMETIC N5-METHYL-N2-(NONANOYL-L-LEUCYL)-L-GLUTAMINATE DERIVATIVES, TRIAZASPIRO[4.14]NONADECANE DERIVATIVES AND SIMILAR COMPOUNDS AS INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION

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Paragraph 00455; 00679-00680, (2021/09/26)

Peptidomimetic N5-methyl-N2-(nonanoyl-L-leucyl)-L-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds for use in methods of inhibiting the replication of noroviruses and coronaviruses in a biological sample or patient, for use in reducing the amount of noroviruses or coronaviruses in a biological sample or patient, and for use in treating norovirus and coronavirus in a patient, comprising administering to said biological sample or patient a safe and effective amount of a compound represented by formulae I or II, or a pharmaceutically acceptable salt thereof. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. page 99 to page 271; examples 1 to 3; compounds A1 to A104 and Bl to B66; tables A to E).

Antirheumatic agents. III. Novel methotrexate derivatives bearing an indoline ring and a modified ornithine or glutamie acid

Matsuoka, Hiroharu,Kato, Nobuaki,Ohi, Nobuhiro,Miyamoto, Katsuhito,Mihara, Masahiko,Takeda, Yasuhisa

, p. 1146 - 1150 (2007/10/03)

The synthesis, biological profile and structure-activity relationship of various methotrexate (MTX) derivatives bearing an indoline ring are described. In particular, Nδ-(3-carboxyphenyl)-Nα-[1-[(2,4-diaminopteridin- 6-yl)methyl]indoline-5-ylcarbonyl]-L-glutamine (3d), compared to MTX; exhibited an enhanced anti-proliferative effect on human peripheral blood mononuclear cells obtained from healthy volunteers.

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