19427-11-3

Upstream product

• 21086-33-9 2-bromo-1-(4-methoxyphenyl)-1-propanone 
• 1074-82-4 potassium phtalimide 
• 100-66-3 methoxybenzene 
• 21860-84-4 2-phthalimidopropionic acid 

Downstream Products

• 139016-51-6 2-[2-[(E)-Hydroxyimino]-2-(4-methoxy-phenyl)-1-methyl-ethyl]-isoindole-1,3-dione 
• 139016-58-3 ethyl <6-amino-4-<<2-(4-methoxyphenyl)-1-methyl-2-oxoethyl>amino>-5-nitropyridin-2-yl>carbamate oxime 
• 143858-98-4 2-amino-4'-methoxypropiophenone oxime 

Relevant academic research and scientific papers

Antimitotic agents. Chiral isomers of ethyl [5-amino-1,2-dihydro-3-(4- hydroxyphenyl)-2-methylpyrido[3,4-b]pyrazin-7-yl]carbamate

Metabolism studies with ethyl [5-amino-1,2-dihydro-2-methyl-3- phenylpyrido[3,4-b]pyrazin-7-yl]carbamate (1) in mice were reported previously to give a hydroxylated metabolite, which was methylated to give a methoxy derivative. The metabolite and its deri

Ferric Chloride-Catalyzed Acylation of Aromatic Compounds with N-Phthaloyl-α-amino Acyl Chlorides without Racemisation

Reactive aromatic compounds are acylated without racemisation to aryl 1-phthalimidoalkyl ketones 4 in good yields with N-phthaloyl-α-amino acid chlorides in the presence of catalytic amounts (1 to 5 mol-percent) of FeCl3.This new method is especially useful for the synthesis of the pharmacologically interesting alkoxyaryl 1-phthalimidoalkyl ketones 6, 8, 10, and 11, which cannot be prepared in reasonable yields in the presence of other FC catalysts such as AlCl3 or SnCl4.