194290-78-3Relevant academic research and scientific papers
Acyclo C-nucleosides analogues of condensed 1,2,4-triazines
El Ashry, El Sayed H.,Rashed, Nagwa,Abdel Hamid, Hamida,Ramadan, El Sayed
, p. 873 - 882 (1997)
1-Acyclo C-nucleosides of 7-methyl-10H-1,2,4-triazolo[3',4':3,4][1,2,4]triazino[5,6-b]indoles (9) have been prepared by cyclodehydrogenation of the sugar derivatives of 3-hydrazino-8-methyl-5H-1,2,4-triazino[5,6-b]indole (1). The respective linear isomer as 4 has been prepared by a dehydrative cyclization of the amides of 1. Acetylation of the sugar hydrazones and their cyclized products gave the per-N,O-acetyl derivatives. The molecular connectivity of the products was established by 1H, 13C, and 2D H,H Cosy spectra.
