19432-66-7Relevant academic research and scientific papers
Practical preparation of ethyl 2-methylthiophene-3-carboxylate
Kogami, Masakazu,Watanabe, Nobuhide
, p. 797 - 798 (2011)
A safe and efficient process for the preparation of ethyl 2-methylthiophene-3-carboxylate (5) was devised. This process provides several advantages over the precedents, involving operational simplicity, avoidance of the use of strong bases such as n-butyllithium and application of noncryogenic conditions, and enabled to prepare 5 in 52% overall yield from commercially available 2-methylthiophene on a multikilogram scale.
PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS
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Page/Page column 69, (2022/02/05)
Compounds of the formula (I) wherein the substituents are as defined in claim 1. Furthermore, the present invention relates to agrochemical compositions which comprise compounds of formula (I), to preparation of these compositions, and to the use of the compounds or compositions in agriculture or horticulture for combating, preventing or controlling animal pests, including arthropods and in particular insects, moluscs, nematodes or representatives of the order Acarina.
Convenient method for the preparation of the 2-methyl thiophen-3-yl magnesium bromide lithium chloride complex and its application to the synthesis of 3-substituted 2-methylthiophenes
Kogami, Masakazu,Watanabe, Nobuhide
, p. 681 - 688 (2013/01/15)
Lithium chloride was found to accelerate formation of the Grignard reagent from inactive 3-bromo-2-methylthiophene (1) and commercial magnesium metal. Based on this finding, a convenient and potentially scalable preparation of ethyl 2-methylthiophene-3-ca
Phosphorylamides, their preparation and use
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, (2008/06/13)
A phosphorylamide derivative represented by the general formula (I): STR1 wherein R represents an amino group that may be substituted, or a salt thereof, possesses potent antibacterial activity against Helicobacter bacterium, especially Helicobacter pylori, and is useful for prevention or treatment of digestive diseases caused by Helicobacter bacterium, solely or in combination with an antacid or an acid secretion inhibitor.
Preparation of 2,3-Disubstituted-4,5-dihydrothiphenes and Thiophenes Using the Intramolecular Non-classical Wittig Reaction of Thiocarboxylates
Chatterjee, Pallab,Murphy, Patrick J.,Pepe, Rosanna,Shaw, Michael
, p. 2403 - 2406 (2007/10/02)
2-Ethoxycarbonylcyclopropyl(triphenyl)phosphonium fluoroborate 1 reacts with alkali-methal thiolates to give 2,3-disubstituted 4,5-dihydrothiophnes 3 which can be aromatised to the corresponding thiophenes 5.
