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Uridine, 2'-deoxy-5-(1-pyrenylethynyl)-, 3',5'-diacetate, also known as Pyrrolo-dC-DA, is a modified nucleoside analog characterized by the attachment of a pyrene group to the base of the nucleoside. This chemical modification endows the compound with fluorescent properties, allowing it to be used as a probe in molecular biology and biochemistry. The diacetate groups on the 3' and 5' positions enhance its solubility in organic solvents, broadening its applicability in various experimental settings. Pyrrolo-dC-DA is a valuable tool for studying the structure, function, and dynamics of nucleic acids and their interactions with proteins within the cell.

194341-95-2

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194341-95-2 Usage

Uses

Used in Molecular Biology and Biochemistry Research:
Uridine, 2'-deoxy-5-(1-pyrenylethynyl)-, 3',5'-diacetate is used as a fluorescent probe for investigating nucleic acid structure, function, and dynamics within the cell. Its fluorescence emission upon interaction with certain biological molecules makes it a useful tool for tracking and analyzing nucleic acid behavior and interactions.
Used in Drug Development and Screening:
In the pharmaceutical industry, Pyrrolo-dC-DA can be employed as a component in drug screening assays to identify potential therapeutic agents that interact with nucleic acids. Its fluorescent properties allow for the monitoring of drug-nucleic acid interactions, facilitating the discovery of new drugs with specific binding affinities.
Used in Diagnostic Applications:
Pyrrolo-dC-DA can be utilized in the development of diagnostic tools for detecting and monitoring diseases associated with nucleic acid abnormalities. Its ability to fluoresce upon binding to target nucleic acid sequences can be harnessed to create sensitive and specific diagnostic assays.
Used in Bioimaging Techniques:
In the field of bioimaging, Uridine, 2'-deoxy-5-(1-pyrenylethynyl)-, 3',5'-diacetate serves as a fluorescent label for visualizing nucleic acids in living cells or tissues. This allows researchers to study the spatial distribution and dynamics of nucleic acids in real-time, providing insights into cellular processes and mechanisms.
Used in Nanotechnology and Materials Science:
The unique properties of Pyrrolo-dC-DA, such as its fluorescence and solubility, make it a candidate for the development of novel nanomaterials and biocompatible materials with potential applications in sensing, imaging, and drug delivery systems.

Check Digit Verification of cas no

The CAS Registry Mumber 194341-95-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,3,4 and 1 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 194341-95:
(8*1)+(7*9)+(6*4)+(5*3)+(4*4)+(3*1)+(2*9)+(1*5)=152
152 % 10 = 2
So 194341-95-2 is a valid CAS Registry Number.

194341-95-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Acetic acid (2R,3S,5R)-2-acetoxymethyl-5-(4-hydroxy-2-oxo-5-pyren-1-ylethynyl-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:194341-95-2 SDS

194341-95-2Upstream product

194341-95-2Relevant academic research and scientific papers

New pyrene derivatives for fluorescent labeling of oligonucleotides

Korshun,Prokhorenko,Gontarev,Skorobogatyi,Balakin,Manasova,Malakhov,Berlin

, p. 1461 - 1464 (1997)

A series of pyrene-containing reagents have been synthesized and used for the fluorescent labeling of oligonucleotides.

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