297730-65-5

Upstream product

• 34993-56-1 1-ethynylpyrene 
• 215451-63-1 3-(1-pyrenyl)-3-chloro-2-propenal 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 194341-96-3 5-(1-pyrenylethynyl)-2'-deoxyuridine 
• 104375-88-4 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-iodouridine 
• 194341-95-2 Acetic acid (2R,3S,5R)-2-acetoxymethyl-5-(4-hydroxy-2-oxo-5-pyren-1-ylethynyl-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 
• 194341-96-3 4-Hydroxy-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-pyren-1-ylethynyl-1H-pyrimidin-2-one 

Relevant academic research and scientific papers

Synthesis and fluorescent properties of 5-(1-pyrenylethynyl)-2′-deoxyuridine-containing oligodeoxynucleotides

Novel reagents for the fluorescent labeling of oligo- and polynucleotides have been prepared: 5-(1-pyrenylethynyl)-2′-deoxyuridine 3′-phosphoramidite and a solid support carrying this nucleoside. Oligonucleotides containing one or several modified units have been synthesized, and the fluorescence of these probes has been shown to change upon hybridization with the complementary sequence.

New pyrene derivatives for fluorescent labeling of oligonucleotides

A series of pyrene-containing reagents have been synthesized and used for the fluorescent labeling of oligonucleotides.