194350-88-4

Basic information

• Product Name: 1-methylpiperazin-2-one trifluoroacetate
• Synonyms: 1-methylpiperazin-2-one trifluoroacetate;2-piperazinone, 1-methyl-, trifluoroacetate (1:1);1-methylpiperazin-2-one 2,2,2-trifluoroacetate
• CAS NO: 194350-88-4
• Molecular Formula: C₂HF₃O₂*C₅H₁₀N₂O
• Molecular Weight: 228.1690496
• Mol File: 194350-88-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-methylpiperazin-2-one trifluoroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methylpiperazin-2-one trifluoroacetate(194350-88-4)
• EPA Substance Registry System: 1-methylpiperazin-2-one trifluoroacetate(194350-88-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 194350-88-4(Hazardous Substances Data)

Usage

Chemical structure

A piperazine ring with a methyl group and a carbonyl group attached.

Salt form

Trifluoroacetate salt.

Common usage

Used in chemical reactions and organic synthesis.

Versatility

A versatile intermediate with a wide range of applications in pharmaceuticals, agrochemicals, and material science.

Upstream product

• 109384-27-2 1-methylpiperazin-2-one hydrochloride 
• 109384-26-1 1-tert-butoxycarbonyl-4-methyl-3-oxopiperazine 
• 76-05-1 trifluoroacetic acid 

Downstream Products

• 862728-36-7 trans-{4-[4-(4-amino-5-iodo-pyrazolo[2,3-d]pyrimidin-7-yl)-cyclohexyl]}-1-methyl-piperazin-2-one 

Relevant articles and documents

PYRAZOLE DERIVATIVES

A compound represented by formula (I): (wherein Ar1 represents a phenyl group which may have 1 to 3 substituents, or a non-substituted 5- or 6-membered aromatic heterocyclic group; Ar2 represents (i) a non-substituted phenyl group, (ii) a phenyl group which has been substituted by a lower alkyl group having 1 to 3 groups or atoms selected from among a carbamoyl group, an amino group, a hydroxyl group, a lower alkoxy group, and a halogen atom, or (iii) a 5- or 6-membered nitrogen-containing aromatic heterocyclic group which has been substituted by 1 to 3 groups or atoms selected from among a lower alkyl group, a lower alkynyl group, a lower alkanoyl group, a carbamoyl group, a cyano group, an amino group, a hydroxyl group, a lower alkoxy group, and a halogen atom; and X represents a group represented by formula (II): (wherein the ring structure represents a 4- to 7-membered heterocyclic group which may have, in addition to the nitrogen atom shown in formula (II), one heteroatom selected from among nitrogen, oxygen, and sulfur, and which may be substituted by 1 to 4 groups or atoms selected from among a lower alkyl group, a carbamoyl group, an amino group, a hydroxyl group, a lower alkoxy group, an oxo group, a lower alkanoyl group, a lower alkylsulfonyl group, and a halogen atom)), a salt thereof, a solvate of the compound or the salt, and a drug.

FIVE-MEMBERED HETEROCYCLIC DERIVATIVE

The present invention relates to a compound represented by formula (I): a salt of the compound, or a solvate of the compound or the salt; a drug containing any of the compounds, the salts, and the solvates; a preventive and/or therapeutic agent for an ischemic disease containing any of the compounds, the salts, and the solvates; and a platelet coagulation inhibitor containing any of the compounds, the salts, and the solvates. The compound of the present invention is useful as a strong platelet coagulation inhibitor without inhibiting COX-1 or COX-2.