194420-17-2

Basic information

• Product Name: 2α,10β-dibenzyloxy-11β-(t-butyldimethylsiloxy)-7β-hydroxy-1α-(p-methoxybenzyloxy)-8β,15,15-trimethyl-4-methylene-trans-bicyclo[6.4.0]dodecan-9-one
• Synonyms: 2α,10β-dibenzyloxy-11β-(t-butyldimethylsiloxy)-7β-hydroxy-1α-(p-methoxybenzyloxy)-8β,15,15-trimethyl-4-methylene-trans-bicyclo[6.4.0]dodecan-9-one
• CAS NO: 194420-17-2
• Molecular Weight: 729.042
• Mol File: 194420-17-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2α,10β-dibenzyloxy-11β-(t-butyldimethylsiloxy)-7β-hydroxy-1α-(p-methoxybenzyloxy)-8β,15,15-trimethyl-4-methylene-trans-bicyclo[6.4.0]dodecan-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2α,10β-dibenzyloxy-11β-(t-butyldimethylsiloxy)-7β-hydroxy-1α-(p-methoxybenzyloxy)-8β,15,15-trimethyl-4-methylene-trans-bicyclo[6.4.0]dodecan-9-one(194420-17-2)
• EPA Substance Registry System: 2α,10β-dibenzyloxy-11β-(t-butyldimethylsiloxy)-7β-hydroxy-1α-(p-methoxybenzyloxy)-8β,15,15-trimethyl-4-methylene-trans-bicyclo[6.4.0]dodecan-9-one(194420-17-2)

Safety Data

• Hazardous Substances Data: 194420-17-2(Hazardous Substances Data)

Upstream product

• 194420-16-1 4-[(1S,2S,3R,5R,6R,8S)-2,6-Dibenzyloxy-5-(tert-butyldimethylsiloxy)-3-(p-methoxybenzyloxy)-4,4,8-trimethyl-7-oxocyclooctyl]-4-pentenal 
• 194420-13-8 (2R,3R,5R,6R,8R*)-2,6-Dibenzyloxy-8-bromo-5-(tert-butyldimethylsiloxy)-3-(p-methoxybenzyloxy)-4,4-dimethyl-7-oxononanol 
• 194420-15-0 (2R,3R,5R,6S,7S,8S)-2,6-Dibenzyloxy-3-(tert-butyldimethylsiloxy)-5-(p-methoxybenzyloxy)-4,4,8-trimethyl-7-{1-[3-(triethylsiloxy)propyl]vinyl}cyclooctanone 
• 222726-93-4 (2R,3R,5R,6S,7S,8S)-2,6-Dibenzyloxy-3-(tert-butyldimethylsiloxy)-7-[1-(3-hydroxypropyl)vinyl]-5-(p-methoxybenzyloxy)-4,4,8-trimethylcyclooctanone 
• 178626-24-9 2-bromo-5-(triethylsilyloxy)pentene 
• 35804-44-5 ethyl 4-bromo-4-pentenoate 
• 64180-78-5 4-bromopent-4-en-1-ol 
• 194420-18-3 (1S,3R,4R,6R,7S,8R,12R)-3,7-Dibenzyloxy-4-(tert-butyldimethylsiloxy)-12-hydroxy-6-(p-methoxybenzyloxy)-1,5,5-trimethyl-9-methylenebicyclo[6.4.0]dodecan-2-one 

Downstream Products

• 248252-86-0 [(3aS,6aR,7S,8R,10R,11S,11aR,11bS)-7,11-Bis-benzyloxy-8-(4-methoxy-benzyloxy)-2,2,9,9,11b-pentamethyl-6-methylene-dodecahydro-1,3-dioxa-cycloocta[de]naphthalen-10-yloxy]-tert-butyl-dimethyl-silane 
• 248252-92-8 (3aS,6aR,7S,8S,11S,11aR,11bS)-7,11-Bis-benzyloxy-8-(ethyl-dimethyl-silanyloxy)-2,2,9,9,11b-pentamethyl-6-methylene-8-(2-oxo-propyl)-decahydro-1,3-dioxa-cycloocta[de]naphthalen-10-one 
• 248252-89-3 (3aS,6aR,7S,8S,11S,11aR,11bS)-8-Allyl-7,11-bis-benzyloxy-8-(ethyl-dimethyl-silanyloxy)-2,2,9,9,11b-pentamethyl-6-methylene-decahydro-1,3-dioxa-cycloocta[de]naphthalen-10-one 
• 248252-88-2 C₃₉H₅₄O₆Si 
• 248252-87-1 (3aS,6aR,7S,10R,11S,11aR,11bS)-7,11-Bis-benzyloxy-10-(tert-butyl-dimethyl-silanyloxy)-2,2,9,9,11b-pentamethyl-6-methylene-decahydro-1,3-dioxa-cycloocta[de]naphthalen-8-one 
• 222726-76-3 2',3'-O,N-[(S)-(p-Methoxybenzylidene)]paclitaxel 
• 194420-21-8 (1R,2S,3S,5R,6S,7S,8S,9S)-2,6-Dibenzyloxy-3-(3-butenyl)-5-(tert-butyldimethylsiloxy)-7,9-(isopropylidenedioxy)-4,4,8-trimethyl-12-methylenebicyclo[6.4.0]dodecan-3-ol 
• 202390-88-3 2',3'-O,N-[(S)-(p-Methoxybenzylidene)]-7-O-(triethylsilyl)paclitaxel 
• 194420-28-5 2'-O-benzyl-7-O-(triethylsilyl)paclitaxel 
• 194420-23-0 (1S,2S,3S,6S,7S,8R,12S)-3,7-Dibenzyloxy-6-(dicyclohexylmethylsiloxy)-2,12-(isopropylidenedioxy)-1,5,5-trimethyl-9-methylene-6-(3-oxobutyl)bicyclo[6.4.0]dodecan-4-one 
• 222726-98-9 (1S,2S,3S,6S,7S,8R,12S)-3,7-Dibenzyloxy-6-(3-butenyl)-6-(dicyclohexylmethylsiloxy)-2,12-(isopropylidenedioxy)-1,5,5-trimethyl-9-methylenebicyclo[6.4.0]dodecan-4-one 
• 194420-24-1 (4S,4aS,5S,6S,7R,8R,11S,12S,12aR)-6,12-Dibenzyloxy-11-(dicyclohexylmethylsiloxy)-4,5-(isopropylidenedioxy)-4a,8,13,13-tetramethyl-1-methylenetetradecahydro-7,11-methanobenzocyclodecene-7,8-diol 
• 194420-22-9 (1S,2S,3R,4R,6S,7S,8R,12S)-3,7-Dibenzyloxy-6-(3-butenyl)-6-(dicyclohexylmethylsiloxy)-2,12-(isopropylidenedioxy)-1,5,5-trimethyl-9-methylenebicyclo[6.4.0]dodecan-4-ol 
• 202341-03-5 (1S,2S,3S,4R,6S,7S,8R,12S)-3,7-Dibenzyloxy-6-(3-butenyl)-4,6-(dicyclohexylsilylenedioxy)-2,12-(isopropylidenedioxy)-1,5,5-trimethyl-9-methylenebicyclo[6.4.0]dodecane 

Relevant articles and documents

Stereocontrolled synthesis of the BC ring system of Taxol

Optically active 2α,10β-dibenzyloxy-11β-(t-butyldimethylsiloxy)-7β-hydroxy- 1α-(4-methoxybenzyloxy)-8β,15,15-trimethyl-4-methylene-trans- bicyclo[6.4.0]dodecan-9-one 2 that corresponds to BC ring system of Taxol was prepared from 8-membered ring enone 3 i