194426-11-4Relevant academic research and scientific papers
A synthesis of di- and tri-substituted β,γ-unsaturated esters from aldehydes by the magnesium carbenoid 1,2-CH and 1,2-CC insertion as the key reaction
Yamashita, Hironori,Satoh, Tsuyoshi
scheme or table, p. 613 - 627 (2009/04/06)
Addition reaction of 1-chlorovinyl p-tolyl sulfoxides, which were derived from aldehydes, with lithium enolate of tert-butyl acetate at -78 °C in THF gave adducts in high yields. Treatment of these adducts with Grignard reagents resulted in the formation
Stereoselective Horner-Wittig synthesis of (Z)-1-chlorovinyl sulfoxides
Otten, Pieter A.,Davies, Honorine M.,Van Steenis, Jan Hein,Gorter, Syb,Van Der Gen, Arne
, p. 10527 - 10544 (2007/10/03)
This paper describes the synthesis of (Z)-1-chlorovinyl sulfoxides 1 by the Horner-Wittig reaction. The required [(α-chloro)sulfinylmethyl]diphenylphosphine oxides 2 (R1=Me, c-Hex, Ph, p-Tol, p-(CF3)Ph), were prepared in high yields
