24824-93-9

Upstream product

• 623-13-2 4-methylphenyl methylsulfide 
• 5056-07-5 (S)-methyl p-tolyl sulfoxide 
• 34125-84-3 chloromethyl p-tolyl sulfide 
• 90348-58-6 1,2-Dichlor-1-<4-methyl-phenylsulfoxy>-ethylen 
• 934-72-5 Methyl p-tolyl sulfoxide 

Downstream Products

• 289680-83-7 1-chloro-4-phenyl-1-(p-tolylsulfinyl)-2-butanol 
• 119487-94-4 1-chloro-4-pentenyl p-tolyl sulfoxide 
• 170951-65-2 (Z)-1-chloro-1-(p-tolylsulfinyl)-10-nonadecen-2-one 
• 159763-19-6 6-[Chloro-(toluene-4-sulfinyl)-methyl]-undecan-6-ol 
• 155725-33-0 2-chloro-2-(p-tolylsulfinyl)-1-(2-naphthyl)-1-ethanone 
• 123630-33-1 p-tolyl p-tolyloxymethyl sulphoxide 
• 130650-16-7 1-((Z)-1-Chloro-6-methoxy-hex-5-ene-1-sulfinyl)-4-methyl-benzene 
• 107468-87-1 3-Phenyl-2-(toluene-4-sulfinyl)-1-aza-bicyclo[1.1.0]butane 
• 934-72-5 Methyl p-tolyl sulfoxide 
• 130650-08-7 Trimethyl-[3-(toluene-4-sulfinyl)-propyl]-silane 
• 38010-00-3 α-Metoxymethyl-p-toluylsulfoxid 
• 7569-26-8 chloromethyl p-tolylsulfone 
• 172467-95-7 1-[Chloro-(toluene-4-sulfinyl)-methyl]-cyclopentadecanol 
• 209391-67-3 8-[Chloro-(toluene-4-sulfinyl)-methyl]-1,4-dioxa-spiro[4.5]decan-8-ol 

Relevant academic research and scientific papers

ELECTROPHILIC REAGENTS FOR MONOHALOMETHYLATION,THEIR PREPARATION AND THEIR USES

The invention provides a compound of formula A, B, C or D, methods for making them, intermediates therefor, and their use in making organic biologically active compounds: (Formula (A)). Wherein: ? X = F, CI, Br, I, sulfonate esters, phosphate esters or another leaving group ? R1, R2, R3, R4, R5, R6, R7, R8, R9, R1O are each individually selected from H, alkyl, aryl, alkynyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxy, nitro, halogen or amino; or are selected from H, C1C10 alkyl, aryl, C1C10 alkynyl, C1C10 alkenyl, C1C10 cycloalkyl, C1C10 cycloalkenyl, C1C10 alkoxy, nitro, halogen or amino ? R11 = tetrafluoroborate, triflate, halogen, perclorate, sulfates, phosphates or carbonates ? Excluding the case when: X = F and R1= R2 = R3 = R4= R5 = H and R6 R8 = R9 = methyl, R10 = H and R11 = triflate or tetrafluoroborate; or (Formula (B)). Wherein: X = F, CI, Br, I, sulfonate esters, phosphate esters or other another leaving group; and R1, R2, R3, R4, R5 are each individually selected from H, alkyl, aryl, alkynyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxy, nitro, halogen or amino; or are selected from H, C1C10 alkyl, aryl, C1C10 alkynyl, C1C10 alkenyl, C1C10 cycloalkyl, C1C10 cycloalkenyl, C1C10 alkoxy, nitro, halogen or amino and R11 = tetrafluoroborate, triflate, halogen, perclorate, sulfates, phosphates or carbonates; and R12 = resin, naphthalene or substituted naphthalene Excluding the case when: X = F and R1= R2 = R3 = R4= R5 = H and R6 = R7 = R8 = R9 = methyl, R10 = H and R11 = triflate or tetrafluoroborate and when X = F and R1= R2 = R3 = R4= R5 = H and R12 = poly(styrene-co- divinylbenzene) and R11 = triflate or tetrafluoroborate; or (Formula (C)). Wehrein ? X = F, CI, Br, I, sulfonate esters, phosphate esters or another leaving group ? R13 = naphthalene or substituted naphthalene ? R6, R7, R8, R9, R10 are each individually selected from H, alkyl, aryl, alkynyl, alkenyl, cycloalkyl, cycloalkenyl, alcoxy, nitro, halogen or amino; or are selected from H, C1C10 alkyl, aryl, C1C10 alkynyl, C1C10 alkenyl, C1C10 cycloalkyl, C1C10 cycloalkenyl, C1C10 alkoxy, nitro, halogen or amino ? R11 = tetrafluoroborate, triflate, halogen, perclorate, sulfates, phosphates or carbonates: or (Formula (D)) X = F, CI, Br, I, sulfonate esters, phosphate esters or another leaving group R13 = naphthalene or substituted naphthalene R11 = tetrafluoroborate, triflate, halogen, perclorate, sulfates, phosphates carbonates R12 = resin, naphthalene or substituted naphthalene.

Nitric acid in the presence of supported P2O5 on silica gel affords an efficient and mild system for oxidation of organic compounds under solvent-free conditions

This paper describes an efficient and easy method for oxidation of alcohols 1 and sulfides 2 to their corresponding carbonyl compounds 3 and sulfoxides 4 with nitric acid in the presence of supported P2O5 on silica gel under solvent-free conditions in high yields.

Nitric acid in the presence of supported P2O5 on silica gel: An efficient and novel reagent for oxidation of sulfides to the corresponding sulfoxides

This paper describes an efficient and easy method for oxidation of sulfides 1 to their corresponding sulfoxides 2 with nitric acid in the presence of supported P2O5 on silica gel under solvent-free conditions in high yields.

1-Butyl-4-aza-1-azoniabicyclo[2.2.2]octane dichromate (BAAOD): An efficient and novel reagent for oxidation of sulfides to the corresponding sulfoxides

This article describes an efficient and easy method for oxidation of sulfides 1 to their corresponding sulfoxides 2 with 1-butyl-4-aza-1- azoniabicyclo[2.2.2]octane dichromate (BAAOD) under nonaqueous conditions in high yields.

α-Phosphoryl Sulfoxides VIII. Stereochemistry of α-Chlorination of α-Phosphoryl Sulfoxides

Chlorination of α-phosphoryl sulfoxides 1 with iodobenzene dichloride and sulfuryl chloride in the presence and in the absence of pyridine and stereochemical investigations of this reaction using (+)-(S)-α-dimethoxyphosphorylmethyl p-tolyl sulfoxide 1a ar

Facile one-pot synthesis of α-chloro sulfoxides from sulfides

Various sulfides 1 reacted with sulfuryl chloride in the presence of metal nitrates in acetonitrile under mild conditions to give the corresponding α-chloro sulfoxides 2 in good yields.

Solid-Phase Silica-Gel Catalyzed α-Halogenation of Alkyl Aryl Sulfoxides with N-Halosuccinimides

Alkyl aryl sulfoxides are readily halogenated by silica-gel supported N-halosuccinimides.The conversion of optically active alkyl 4-methylphenyl sulfoxides into 1-haloalkyl 4-methylphenyl sulfoxides is accompanied by inversion of configuration at the S-atom.The stereoselectivity of the solid-phase halogenation of alkyl aryl sulfoxides is much higher than that observrd for the halogenation in solution.