194427-24-2

Basic information

• Product Name: Cyclohexanemethanol, 4,4-difluoro-, methanesulfonate
• CAS NO: 194427-24-2
• Molecular Formula: C8H14F2O3S
• Molecular Weight: 228.26
• Mol File: 194427-24-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Cyclohexanemethanol, 4,4-difluoro-, methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanemethanol, 4,4-difluoro-, methanesulfonate(194427-24-2)
• EPA Substance Registry System: Cyclohexanemethanol, 4,4-difluoro-, methanesulfonate(194427-24-2)

Safety Data

• Hazardous Substances Data: 194427-24-2(Hazardous Substances Data)

Upstream product

• 178312-48-6 (4,4-difluorocyclohexyl)methanol 
• 124-63-0 methanesulfonyl chloride 
• 122665-97-8 4,4-difluorocyclohexanecarboxylic acid 
• 121629-14-9 methyl 4,4-difluorocyclohexane-1-carboxylate 

Downstream Products

• 949904-67-0 acetic acid [(4,4-difluoro-cyclohexylmethyl)-(2-oxo-ethyl)-carbamoyl]-methyl ester 
• 1122649-27-7 3-endo-{8-[1-(4,4-difluorocyclohexylmethyl)-1H-imidazol-4-ylmethyl]-8-azabicyclo[3.2.1]oct-3-yl}benzamide 
• 1122649-24-4 3-endo-{8-[3-(4,4-difluorocyclohexylmethyl)-3H-imidazol-4-ylmethyl]-8-azabicyclo[3.2.1]oct-3-yl}benzamide 
• 1123661-37-9 2-[(4,4-difluorocyclohexylmethyl)amino]ethanol 

Relevant articles and documents

HYDROXYL PURINE COMPOUNDS AND USE THEREOF

Disclosed are a series of hydroxyl purine compounds and the use thereof as PDE2 or TNFα inhibitors, in particular, the compounds as shown in formula (I), or tautomers thereof or pharmaceutically acceptable salts thereof.

BIS(SULFONAMIDE) DERIVATIVES AND THEIR USE AS MPGES INHIBITORS

The present invention relates to bis(sulfonamide) compounds and pharmaceutically acceptable salts thereof. The present invention also relates to pharmaceutical compositions comprising these compounds and to their use as a medicament for the treatment and/or prevention of a disease, disorder or condition in which modulation of microsomal prostaglandin E synthase-1 activity is beneficial, such as pain, inflammation and cancer.

ALKOXY COMPOUNDS FOR DISEASE TREATMENT

The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.