194468-64-9Relevant academic research and scientific papers
7-Spirobenzocyclohexyl derivatives of naltrexone, oxymorphone, and hydromorphone as selective opioid receptor ligands
Fang, Xinqin,Larson, Dennis L.,Portoghese, Philip S.
, p. 3064 - 3070 (2007/10/03)
On the basis of previous structure-activity studies of the highly potent and selective δ-opioid receptor antagonist naltrindole (1) and the spiroindanyl analagues 2 and 3, we have synthesized epimeric pairs of spirobenzocyclohexyl derivatives of naltrexon
