194490-33-0 Usage
Description
Methyl 3-cyano-1H-indole-5-carboxylate is a chemical compound with the molecular formula C13H10N2O2. It is a derivative of indole, a heterocyclic organic compound that is commonly found in various natural products and pharmaceuticals. Methyl 3-cyano-1H-indole-5-carboxylate is a yellow-to-orange solid and is widely recognized for its role as a building block in organic synthesis.
Uses
Used in Pharmaceutical Industry:
Methyl 3-cyano-1H-indole-5-carboxylate is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and versatile chemical properties make it valuable for the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, Methyl 3-cyano-1H-indole-5-carboxylate is utilized as a precursor in the production of agrochemicals. Its role in this industry is crucial for the synthesis of compounds that can be used in pest control and crop protection, thereby supporting agricultural productivity.
Used in Organic Synthesis:
Methyl 3-cyano-1H-indole-5-carboxylate is used as a versatile intermediate in organic synthesis for the preparation of a wide range of fine chemicals. Its presence in this field is significant for the creation of specialty chemicals used across various industries, including but not limited to pharmaceuticals, materials science, and fragrances.
Safety Precautions:
As with all chemicals, Methyl 3-cyano-1H-indole-5-carboxylate requires proper handling and safety measures to ensure the well-being of those who work with it. Adherence to safety protocols is essential to prevent any potential hazards associated with its use in research and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 194490-33-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,4,9 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 194490-33:
(8*1)+(7*9)+(6*4)+(5*4)+(4*9)+(3*0)+(2*3)+(1*3)=160
160 % 10 = 0
So 194490-33-0 is a valid CAS Registry Number.
194490-33-0Relevant articles and documents
GaCl3-Catalyzed C-H Cyanation of Indoles with N-Cyanosuccinimide
Wang, Xue,Makha, Mohamed,Chen, Shu-Wei,Zheng, Huaiji,Li, Yuehui
, p. 6199 - 6206 (2019/05/24)
An efficient GaCl3-catalyzed direct cyanation of indoles and pyrroles using bench-stable electrophilic cyanating agent N-cyanosuccinimide was achieved and afforded 3-cyanoindoles and 2-cyanopyrroles in good yields and excellent regioselectivities. Notably, this protocol exhibited high reactivity for unprotected indoles and was applicable to a broad range of indole and pyrrole substrates.
Thiazolylbenzofuran derivatives and pharmaceutical compositions containing them
-
, (2008/06/13)
This invention relates to novel thiazolylbenzofuran derivatives of formula (I) wherein R1 is lower alkyl, L is single bond or lower alkylene optionally substituted with aryl, oxo or hydroxy, and Q is a heterocyclic group optionally substituted with one or more suitable substituent(s); or lower alkoxy substituted with aryl which is substituted with one or more suitable substituent(s) and at least one of which is lower alkoxy optionally substituted with cyano, protected carboxy, carboxy, lower alkylene, a heterocyclic group optionally substituted with oxo, or amidino optionally substituted with hydroxy or lower alkoxy, or its salt, which possess activities as leukotriene and SRS-A antagonists or inhibitors.
