194493-22-6Relevant academic research and scientific papers
A radical cyclisation based cyclopentenone annulation of allyl alcohols
Srikrishna,Viswajanani,Sattigeri
, p. 2975 - 2983 (2007/10/03)
A four-step cyclopentenone annulation reaction of allylic alcohols employing a 5-exo-trig radical cyclisation reaction of mixed allyl methyl ketals of bromoacetone as the key step is described. The annulated product 12b obtained from 2,3-dimethylcyclohexenol has been further elaborated into (±)-epibakkenolides employing a 5-exo-dig radical cylisation reaction based α-spiro-β-methylene-γ-butyrolactone annulation methodology.
Tributyltin chloride-sodium cyanoborohydride mediated tandem radical cyclisation-reductive demethoxylation sequence
Srikrishna,Viswajanani,Yelamaggad
, p. 10479 - 10488 (2007/10/03)
Reaction of the bromoketals 3, 7a-g and 11 with tri-n-butyltin chloride and sodium cyanoborohydride in the presence of a catalytic amount of AIBN furnished the ethers 5, 8a-g and 13 via a tandem sequence comprising of a radical cyclisation reaction and tri-n-butylhalostannane and sodium cyanoborohydride mediated reductive demethoxylation of the resulting cyclic ketals.
A new tetrahodrofurannulation via tandem radical cyclisation reaction-reductive deoxygenation sequence
Srikrishna,Viswajanani,Yelamaggad
, p. 1127 - 1128 (2007/10/02)
Treatment of bromoketals 2, derived from allyl alcohols 1, with tributyltin chloride, sodium cyanoborohydride and AlBN furnished the tetrahydrofurannulated products 3 via a 5-exo-trig radical cyclisation reaction followed by reductive cleavage of ketal 4.
