194546-53-7Relevant academic research and scientific papers
Synthesis of (2'S,3'S)-9-(4'-phosphono-4',4'-difluoromethanobutyl)guanine and its enantiomer. Evaluation of the inhibitory activity for purine nucleoside phosphorylase
Yokomatsu, Tsutomu,Sato, Mutsumi,Abe, Hiroshi,Suemune, Kenji,Matsumoto, Keita,Kihara, Taro,Soeda, Shinji,Shimeno, Hiroshi,Shibuya, Shiroshi
, p. 11297 - 11306 (1997)
Conformationally constrained analogues 2a and ent-2a of 9-(difluorophosphonophenyl) guanines 1, a multi-substrate analogue inhibitor of PNP, were prepared from optically active trans-1-(diethoxyphosphinyl)difluromethyl-2-hydroxymethylcyclopropanes (+)-6 a
