Synthesis of (2'S,3'S)-9-(4'-phosphono-4',4'-difluoromethanobutyl)guanine and its enantiomer. Evaluation of the inhibitory activity for purine nucleoside phosphorylase

DOI: 10.1016/S0040-4020(97)00704-7

Source and publish data:

Tetrahedron p. 11297 - 11306 (1997)

Update date:2022-08-03

Topics:

Authors:

Yokomatsu, Tsutomu

Sato, Mutsumi

Abe, Hiroshi

Suemune, Kenji

Matsumoto, Keita

Kihara, Taro

Soeda, Shinji

Shimeno, Hiroshi

Shibuya, Shiroshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(97)00704-7

Conformationally constrained analogues 2a and ent-2a of 9-(difluorophosphonophenyl) guanines 1, a multi-substrate analogue inhibitor of PNP, were prepared from optically active trans-1-(diethoxyphosphinyl)difluromethyl-2-hydroxymethylcyclopropanes (+)-6 a

Full text of DOI:10.1016/S0040-4020(97)00704-7

Products guided by the article

Product name:(1S,2S)-1-(diethoxyphosphinyldifluoro)methyl-2-(4'-toluenesulfonyl)oxymethylcyclopropane

Cas No:194546-53-7

R&D Labs maybe for 194546-53-7

Chengdu Herbpurify Co., Ltd

website:http://www.herbpurify.com

Contact:0086-028-85249238

Address:Room709-C1,Incubator Building, Tianfu Life Science Park No.88,Keyuan Road,Gaoxin district,Chengdu City,Sichuan Prov,China
Jinan Boss Chemical Industry Co., Ltd.【revoke the business license】

website:http://www.chemboss.com.cn

Contact:+86-531-58591595

Address:No2.Hualong Road, Jinan, China
Arshine Pharmaceutical Co., Limited

website:http://www.cnarshine.com

Contact:0731-88503671

Address:Room 1109.Block C3, Lugu Enterprise Plaza,No.27 Wenxuan Road,Changsha National Hi-Tech Industrial Development Zone,Hunan ,P.R.China
DU-HOPE INTERNATIONAL GROUP

Contact:+86-25-52346955

Address:199,JIANYE ROAD,NANJING,CHINA
Zhejiang Chemline International Co., Ltd.

Contact:+86-571-88062298

Address:Hengdian Industry Area, Dongyang, Zhejiang, China

Relevant to this article

Pseudoelement compounds. XI. [1]: Investigations on the coordination behaviour of cyanamidonitrate [NO₂NCN]^-

Doi:10.1002/zaac.19976230821
(1997)
Intermolecular hydrophosphination of alkynes and related carbon-carbon multiple bonds catalyzed by organoytterbiums

Doi:10.1021/jo030163g
(2003)
Synthesis of model tricyclic C-O-D-O-E-F-O-G ring of teicoplanin

Doi:10.1016/S0040-4039(97)01280-X
(1997)
Rhizobial saccharides part 3. Unexpected α-selective glycosylation during synthesis of pyruvated tetrasaccharide fragments related to exopolysaccharides of rhizobium leguminosarum

Doi:10.1080/07328309708006537
(1997)
Synthesis of β-Alkoxy Ketones and α′-Functionalized β-Alkoxy Ketones Utilizing Benzotriazole-Stabilized Acyl Anion Synthons

Doi:10.1021/jo971630v
(1998)
Double insertion of carbon bisulfide into Pb-S bonds of lead(II) bis(arenethiolate): Synthesis and crystal structure of lead(II) bis(aryl trithiocarbonate)

Doi:10.1021/om970861p
(1998)

Article Doi