194672-69-0Relevant academic research and scientific papers
Organocatalytic Conversion of Nucleosides to Furanoid Glycals
Chung, Cheol K.,Ji, Yining,Lam, Yu-Hong,Maligres, Peter E.,Mao, Edna
, p. 7529 - 7536 (2021)
A class of organocatalysts that are highly active for the conversion of 2′-deoxynucleosides to furanoid glycals have been discovered. These phosphorimides, (Ph2PS)2NH and (Ph2PSe)2NH, were shown to effectively mediate persilylation of 2′-deoxynucleosides
Synthesis of erythro and threo furanoid glycals from 1- and 2-phenylselenenyl-carbohydrate derivatives
Bravo, Fernando,Kassou, Mohamed,Diaz, Yolanda,Castillon, Sergio
, p. 83 - 97 (2007/10/03)
Differently protected erythro and threo furanoid glycals were synthesized by selenoxide elimination when phenyl 1-selenoglycosides were treated in oxidizing conditions (tBuOOH, Ti(OiPr)4, Et2iPrN). Th
Facile preparation of protected furanoid glycals from thymidine
Cameron, Melissa A.,Cush, Sarah B.,Hammer, Robert P.
, p. 9065 - 9069 (2007/10/03)
The synthesis of O-silyl- and O-acyl-protected furanose glycals from free thymidine was investigated. The method of glycal formation reported by Pedersen et al. was successfully expanded to include 5-ester (toluoyl) protected glycals as well as various combinations of 5'-ester and 3- and 5- tert-butyldimethylsilyl and tert-butyldiphenylsilyl protection. Gram quantities of furanoid glycals can be prepared in a few days in two-four steps in overall yields ranging from 17 to 80%.
