194713-46-7 Usage
Uses
Used in Pharmaceutical Industry:
2,4-Thiazolidinedione, 5-[[4-[2-(4-oxo-2H-1,3-benzoxazin-3(4H)-yl)ethoxy]phenyl]methyl]is used as a potential antidiabetic agent for the treatment of type 2 diabetes. Its application is based on the compound's ability to improve insulin sensitivity and reduce glucose levels in the body, offering a new approach to managing diabetes.
Used in Research and Development:
In the field of pharmaceutical research and development, 2,4-Thiazolidinedione, 5-[[4-[2-(4-oxo-2H-1,3-benzoxazin-3(4H)-yl)ethoxy]phenyl]methyl]is used as a subject for further investigation to understand its pharmacological properties, potential side effects, and therapeutic efficacy. This research is crucial for determining its viability as a new treatment option for diabetes and possibly other conditions related to insulin resistance or inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 194713-46-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,7,1 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 194713-46:
(8*1)+(7*9)+(6*4)+(5*7)+(4*1)+(3*3)+(2*4)+(1*6)=157
157 % 10 = 7
So 194713-46-7 is a valid CAS Registry Number.
194713-46-7Relevant academic research and scientific papers
Dual PPAR-α and -γ activators derived from novel benzoxazinone containing thiazolidinediones having antidiabetic and hypolipidemic potential
Madhavan, Gurram R.,Chakrabarti, Ranjan,Anantha Reddy,Rajesh,Balraju,Bheema Rao,Rajagopalan,Iqbal, Javed
, p. 584 - 591 (2007/10/03)
2,4-Thiazolidinedione derivatives of 1,3-benzoxazinone were synthesized and evaluated for their PPAR-α and -γ dual activation. DRF-2519, a compound obtained through SAR of TZD derivatives of benzoxazinone, has shown potent dual PPAR activation. In ob/ob mice, it showed better efficacy than the comparator molecules. In fat fed rat model, it showed significant improvement in lipid parameters, which was better than fibrates.
Benzoazine derivative or salt thereof and pharmaceutical compostion comprising the same
-
, (2008/06/13)
A benzoazine derivative represented by the following formula (1), STR1 wherein R1 represents an alkyl group, alkoxy group, halogen atom, halogenoalkyl group, amino group, hydroxy group, benzyloxy group which may have a substituent, cyano group,
