194796-34-4

Upstream product

• 109-97-7 pyrrole 
• 83-38-5 2,6-dichlorobenzaldehyde 
• 194796-31-1 C₁₉H₁₄Cl₂I₂N₂O₄ 
• 194796-32-2 C₁₇H₁₂Cl₂N₂O₄ 

Downstream Products

• 37083-37-7 5,10,15,20-tetrakis(2,6-dichlorophenyl)porphyrin 
• 884530-85-2 hexakis(2,6-dichlorophenyl) [26]hexaphyrin (1.1.1.1.1.1) 

Relevant academic research and scientific papers

C2 symmetric borneol-porphyrin hybrids: Synthesis, characterization, electronic structure and their anti-cancer behaviors

A series of five C2 Symmetric A2B2 type borneol-porphyrin hybrids have been synthesized and characterized. Moreover, a detailed analysis of their optical and redox properties was carried out by comparing the results obtained via optical spectroscopy and electrochemistry. The current results demonstrated that the meso borneol-substitutions excitation coupled strongly with porphyrin core that leads to significant CD signals in the Soret band region, and molecular anti-cancer behaviors were also investigated.

Synthesis and characterization of two novel red-shifted isothiocyanate BODIPYs and their application in protein conjugation

Fluorescent organic small molecules are very important tools for researchers in the fields of biochemistry and biotechnology, and boron-dipyrromethene (BODIPY) class of organic fluorophores gained much attention in recent years due to their remarkable pho

Synthesis of dipyroromethanes in water and investigation of electronic and steric effects in efficiency of olefin epoxidation by sodium periodate catalyzed by manganese tetraaryl and trans disubstituted porphyrin complexes

Condensation of pyrrole with various aldehydes in the presence of BF3?etherate as an acid catalyst in water provides good yield of some dipyrromethanes. Prolongation of the reaction time with aldehydes substituted by electron-donating (mesityl) or electron-withdrawing (2,6-dichlorophenyl) groups on the ortho positions of the phenyl did not lead to decomposition or scrambling. Manganese trans disubstituted porphyrin complexes which derive from various dipyrromethanes and manganese tetraaryl porphyrin complexes including various substituents with different steric and electronic properties show good catalytic activity in epoxidation of alkenes by NaIO4 in the presence of imidazole (ImH). The study of steric and electronic effects of the catalysts on the epoxidation of olefins shows that Mn-porphyrin complexes with more bulky and electron-releasing groups on meso phenyls could increase the epoxidation yield of most alkenes.

Sulfonated graphenes catalyzed synthesis of expanded porphyrins and their supramolecular interactions with pristine graphene

A newer synthesis of sulfonic acid functionalized graphenes have been developed, which have been characterized, examined as heterogeneous solid acid carbocatalyst in the synthesis of selected expanded porphyrins in different reaction conditions. This envi

Synthesis of 5,15-diarylporphyrins via orthoesters condensation with aryldipyrromethanes

General access to 5,15-diarylporphyrins in two steps is described. Generalization of this approach to tetra-substituted porphyrins allows the reproducible preparation of compounds, in some cases with high yields for porphyrins, which can be used in photodynamic therapy (PDT) in cancer today.

Vicarious nucleophilic substitution of α-hydrogen of BODIPY and its extension to direct ethenylation

Direct, oxidizer-free substitution of the 3-hydrogen of BODIPY derivatives has been established through a vicarious nucleophilic substitution procedure. This methodology has been combined with a reversible Michael addition on nitrostyrenes to provide a novel, highly efficient entry to the valuable 3-styrylated BODIPY dyes.

α-/β-formylated boron-dipyrrin (BODIPY) dyes: Regioselective syntheses and photophysical properties

Formylation has been performed on pyrrole-unsubstituted dipyrromethanes 1 and boron-dipyrrin (BODIPY) dyes 4 based on a Vilsmeier-Haack reaction. It is highly regioselective and complementary and occurs exclusively at the α-and β-position, respectively, f

Efficient synthesis of meso-substituted corroles in a H2O-MeOH mixture

New and efficient conditions for the synthesis of meso-substituted corroles were developed. The first step, involving the reaction of aldehydes with pyrrole, was carried out in a water-methanol mixture in the presence of HCl. A relatively narrow distribut

New synthetic models of cytochrome P450: How different are they from the natural species?

Soluble and matrix-bound P450 enzyme models have been synthesized carrying a SO3- ligand coordinating to iron. These complexes display features very similar to cofactors of enzymes such as P450cam with respect to electrochemistry and UV/Vis spectroscopy. Further they catalyze epoxidation reactions with turnover numbers up to 1800. DFT calculations revealed that the coordination of SO3- to Fe(III) produces an active species that displays allylic hydroxylation and epoxidation reactivity patterns that are nearly indistinguishable from those calculated for the natural active species of the enzyme cytochrome P450.

Synthesis and characterization of a new family of iron porphyrins

A significant tool for better understanding the complex nature of the cofactor of heme thiolate proteins such as Cytochromes P450 is the investigation of model compounds. In this context a new family of iron porphyrins has been synthesized by replacing th