194802-05-6

Basic information

• Product Name: N-allyl-N'-cyclohexyl-urea
• CAS NO: 194802-05-6
• Molecular Weight: 182.266
• Mol File: 194802-05-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-allyl-N'-cyclohexyl-urea(CAS DataBase Reference)
• NIST Chemistry Reference: N-allyl-N'-cyclohexyl-urea(194802-05-6)
• EPA Substance Registry System: N-allyl-N'-cyclohexyl-urea(194802-05-6)

Safety Data

• Hazardous Substances Data: 194802-05-6(Hazardous Substances Data)

Upstream product

• 108-91-8 cyclohexylamine 
• 1476-23-9 allylisocyanate 
• 3173-53-3 Cyclohexyl isocyanate 
• 107-11-9 1-amino-2-propene 

Relevant articles and documents

A convenient one-pot synthesis of asymmetric 1,3,5-triazine-2,4,6-triones and its application towards a novel class of gonadotropin-releasing hormone receptor antagonists

A convenient one-pot synthetic route was developed for the preparation of asymmetric 1,3-dialkyl-1,3,5-triazine-2,4,6-triones from readily available alkyl- or aryl-isocyanates, primary amines and N-chlorocarbonyl isocyanate in excellent yields. Subsequent alkylation with N-protected amino alcohols afforded the desired 1,3,5-triazine-2,4,6-triones in good yields. This methodology was applied to the synthesis of a chemical library acting as antagonists of the hGnRH receptor.