19481-83-5

Upstream product

• 4519-46-4 methyl 2-bromoacrylate 
• 908093-98-1 diazodiphenylmethane 
• 13398-28-2 1-Brom-2,2-diphenylcyclopropancarbonsaeure-methylester 
• 124-38-9 carbon dioxide 
• 17343-74-7 1,1-dibromo-2,2-diphenylcyclopropane 
• 530-48-3 1,1-Diphenylethylene 

Downstream Products

• 83198-34-9 (S)-(+)-1-bromo-2,2-diphenyl-cyclopropylcarboxylic acid 
• 7150-12-1 2,2-diphenyl-cyclopropanecarboxylic acid 
• 57719-74-1 1-Bromo-2,2-diphenyl-cyclopropanecarbonyl chloride 
• 37555-48-9 2,2-diphenylcyclopropylmethanol 
• 13398-56-6 (-)-(R)-1-bromo-2,2-diphenylcyclopropanecarboxylic acid 
• 149030-27-3 <(+)-1-Brom-2,2-diphenyl-cyclopropyl>-carbinol 
• 1335201-23-4 1-bromo-N,N-di(but-3-yn-1-yl)-2,2-diphenylcyclopropanecarboxamide 
• 1335201-24-5 N,N-di(but-3-yn-1-yl)-2-methyl-3,3-diphenylacrylamide 
• 1335201-25-6 5-(but-3-yn-1-yl)-8-methylene-1,1-diphenyl-5-azaspiro[2.5]octan-4-one 
• 1335201-33-6 1-bromo-N-(4-methoxybenzyl)-2,2-diphenyl-N-(prop-2-yn-1-yl)cyclopropanecarboxamide 
• 1335201-43-8 2-(4-methoxybenzyl)-9-phenyl-2,3,9,10-tetrahydrobenzo[4,5]cyclohepta[1,2-c]pyrrol-1(4H)-one 
• 1335201-10-9 1-bromo-2,2-diphenyl-N,N-di(prop-2-yn-1-yl)cyclopropanecarboxamide 
• 1335201-11-0 9-phenyl-2-(prop-2-yn-1-yl)-2,3,9,10-tetrahydrobenzo[4,5]cyclohepta[1,2-c]pyrrol-1(4H)-one 
• 1335201-13-2 7-methylene-1,1-diphenyl-5-(prop-2-yn-1-yl)-5-azaspiro[2.4]heptan-4-one 

Relevant academic research and scientific papers

Preparative resolution of bromocyclopropylcarboxylic acids

A general and efficient method for the preparative resolution of α- and β-bromocyclopropylcarboxylic acids has been developed. This protocol involves a sequence of two crystallizations with pseudo-enantiomeric amines, cinchonine, and cinchonidine, which yield both enantiomers of the acid in highly enriched form. Both alkaloids can be easily recovered and reused multiple times without any loss of efficacy.

Incremental solvation precedes ion-pair separation in enantiomerization of a cyano-stabilized Grignard reagent

Concerted or stepwise? Ion-pair separation is often proposed as a mechanism for enantiomerization of organolithium reagents in ethereal solvents. But what is the timing of the solvation and bond-cleavage events? Are they concerted, or does one precede the

Bromine-magnesium exchange in gem-dibromocyclopropanes using Grignard reagents

Reaction of gem-dibromocyclopropanes with ethylmagnesium bromide at ambient temperature leads to very high yields of allenes; when cyclopropylidene-allene ring opening is suppressed, alternative carbenic products are observed, although other reactions compete. When the reactions are carried out at -60°C, a 1-bromo-1-(bromomagnesio)-cyclopropane is formed which may be trapped by a number of electrophiles.