19482-09-8

Upstream product

• 591-50-4 iodobenzene 
• 116632-41-8 1-chloro-4-iodo-2-methylbenzene 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 161950-10-3 4-chloro-3-methylbenzeneboronic acid 
• 54932-72-8 2-chloro-5-bromotoluene 
• 98-80-6 phenylboronic acid 
• 59-50-7 4-Chloro-3-methylphenol 

Relevant academic research and scientific papers

Dichloroimidazolidinedione-activated one-pot Suzuki–Miyaura cross-coupling of phenols

The first general method for the Suzuki-type cross-coupling of phenols with aryl boronic acids using dichloroimidazolidinedione (DCID) as a new reagent is presented. In the presence of DCID and Pd/metal–organic framework (MOF), coupling of aryl boronic acids with a wide range of phenols, was carried out smoothly in tetrahydrofuran (THF) at reflux conditions to afford the cross-coupling products in good to excellent yields. The structures of all compounds were corroborated by 1H- and 13C-NMR. A plausible mechanism for this type of reaction is proposed.

Polymer-Assisted Solution-Phase (PASP) Suzuki Couplings Employing an Anthracene-Tagged Palladium Catalyst

A general method for polymer-assisted solution-phase (PASP) Suzuki reactions employing a combination of anthracene-tagged palladium catalyst and anthracene-tagged boronic acid with a polymer-supported carbonate base is reported. The anthracene-tagged catalyst allows for the easy removal of the Pd catalyst along with the dissociated phosphine ligand and phosphine oxide byproducts by sequestration through a chemoselective Diels-Alder reaction with a maleimide resin. The polymer-supported carbonate base facilitates the removal of excess boronic acid and the borane-containing byproducts present at the end of the coupling reaction. The Suzuki coupling reaction can be efficiently conducted by using combinations of the anthracene-tagged Pd catalyst, polymer-supported carbonate base, and anthracene-tagged boronic acid to yield the desired product in high purity and yield without the use of chromatography.

Difluoromethyltriazolone compounds, use of the same and intermediates for the production thereof

A triazolone compound of the formula [I]: wherein; R1 represents optionally substituted phenyl or the like, T represents m-phenylene optionally substituted by methyl or the like; and a fungicidal composition containing it as an active ingredient.