194861-23-9

Basic information

• Product Name: 2H-Pyran, 3,4-dihydro-2-[(phenylmethoxy)methyl]-
• CAS NO: 194861-23-9
• Molecular Formula: C13H16O2
• Molecular Weight: 204.269
• Mol File: 194861-23-9.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 2H-Pyran, 3,4-dihydro-2-[(phenylmethoxy)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran, 3,4-dihydro-2-[(phenylmethoxy)methyl]-(194861-23-9)
• EPA Substance Registry System: 2H-Pyran, 3,4-dihydro-2-[(phenylmethoxy)methyl]-(194861-23-9)

Safety Data

• Hazardous Substances Data: 194861-23-9(Hazardous Substances Data)

Upstream product

• 756524-92-2 ((2-(allyloxy)pent-4-enyloxy)methyl)benzene 
• 64-17-5 ethanol 
• 1057657-69-8 C₁₅H₂₀O₄ 
• 3540-36-1 (3,4-dihydro-2H-pyran-2-yl)methyl 3,4-dihydro-2H-pyran-2-carboxylate 
• 796077-38-8 benzyloxy-acetic acid butyl ester 
• 100-39-0 benzyl bromide 
• 58931-16-1 1-(benzyloxy)-4-penten-2-ol 
• 60656-87-3 benzyloxyacetoaldehyde 
• 3749-36-8 2-hydroxymethyl-3,4-dihydro-2H-pyran 
• 100-44-7 benzyl chloride 

Downstream Products

• 1426132-74-2 N-(5-(5-(5,5-difluorotetrahydro-2H-pyran-2-yl)-1,2,4-oxadiazol-3-yl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide 
• 1239018-95-1 6-((benzyloxy)methyl)dihydro-2H-pyran-3(4H)-one 
• 1426136-48-2 2-(benzyloxymethyl)-5,5-difluorotetrahydro-2H-pyran 

Relevant articles and documents

Photoinduced Fragmentation Borylation of Cyclic Alcohols and Hemiacetals

A visible-light photoinduced fragmentation borylation of O-phthalimido cycloalkanols with bis(catecholato)diboron is described. Structurally diverse keto and formyloxy alkyl boronic esters are shown to be conveniently prepared by radical-mediated ring opening of cyclic alcohols and hemiacetals, respectively. The reactions proceed under mild conditions in the absence of additives or photocatalysts, display excellent functional group tolerance, and are shown to allow cleavage of 4-, 5-, 6-, and 7-membered ring substrates. The mechanism proceeds via sequential homolytic N-O and C-C bond cleavages, the latter of which involves β-scission of an alkoxy radical, generating a carbonyl and an alkyl radical that is trapped by the diboron reagent. Spectroscopic studies suggest direct photoexcitation of either the phthalimide or diboron substrates with blue light can initiate a radical chain mechanism.

DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA

Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORy. Also provided are pharmaceutical compositions co

Direct C-H Trifluoromethylation of Glycals by Photoredox Catalysis

A mild, efficient, and practical transformation for the direct C-H trifluoromethylation of glycals under visible light has been reported for the first time. This reaction employed fac-Ir3+(ppy)3 as the photocatalyst, Umemoto's reagent as the CF3 source, and a household blue LED or sunlight as the light source. Glycals bearing both electron-withdrawing and -donating protective groups performed this reaction smoothly. This visible light-mediated trifluoromethylation reaction was highlighted by the trifluoromethylation of the biologically important Neu2en moiety.