19487-11-7Relevant academic research and scientific papers
Electrochemical chlorination and bromination of electron-deficient C[sbnd]H bonds in quinones, coumarins, quinoxalines and 1,3-diketones
Yu, Dan,Ji, Ruixue,Sun, Zhihui,Li, Wenjie,Liu, Zhong-Quan
supporting information, (2021/11/16)
The electrochemistry-promoted chlorination and bromination of electron-deficient C[sbnd]H bonds was developed, using quinones, coumarins, quinoxalines and 1,3-diketones. This protocol features readily available and safe halogen sources (hydrochloric acid and KBr), high site-selectivity and mild reaction conditions. It could provide an efficient access to a series of chlorinated and brominated quinones, coumarins, quinoxalines and 1,3-diketones.
Regioselective Oxidative Chlorination of Arenols Using NaCl and Oxone
Uyanik, Muhammet,Sahara, Naoto,Ishihara, Kazuaki
supporting information, p. 27 - 31 (2018/10/25)
We developed a practical and environmentally benign method for the chlorinative dearomatization of arenols using transient electrophilic chlorinating species generated in situ from inexpensive sodium chloride and Oxone as a Cl source and oxidant, respectively, under mild conditions. Moreover, the regioselective chlorination or chlorinative dearomatization of 1-naphthols was also achieved by changing the reaction conditions.
The Chlorination of 2-t-Butyl-4,6-dimethylphenol and 2,6-Di-t-butyl-4-methylphenyl. The Formation of 5,6-Dichloro-4-methylenecyclohex-2-enones
Hartshorn, Michael P.,Judd, Maurice C.,Robinson, Ward T.
, p. 2121 - 2143 (2007/10/02)
The chlorination in acetic acid of 2-t-butyl-4,6-dimethylphenyl (1) gives two chloromethylene compounds (4) and (5), and trichloro ketones (6) and (7).In contrast, 2,6-di-t-butyl-4-methylphenol (2) gives six chlorination products (14)-(19).The notable fea
