194925-84-3 Usage
General Description
The chemical compound "2H-Pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione, 4-methyl-2-(phenylmethyl)-, (4S)-" is a specific stereoisomer of a quinazoline derivative with a pyrazino backbone. It contains a 4-methyl-2-(phenylmethyl) substituent, and its stereochemistry is defined as (4S). 2H-Pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione,
4-methyl-2-(phenylmethyl)-, (4S)- may have potential pharmacological activity due to its unique structure, and it could be of interest for research in medicinal chemistry or drug development. Further investigation into its properties and potential applications may provide valuable insights into its biological effects and therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 194925-84-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,9,2 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 194925-84:
(8*1)+(7*9)+(6*4)+(5*9)+(4*2)+(3*5)+(2*8)+(1*4)=183
183 % 10 = 3
So 194925-84-3 is a valid CAS Registry Number.
194925-84-3Relevant articles and documents
Intramolecular friedel-crafts-type reactions involving N-acyliminium ions derived from glycine templates
Sanchez,Ramos,Avendano
, p. 5731 - 5735 (2007/10/03)
Enantiomerically pure 4-substituted 2-aralkyl-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones (1b-m) in which the alkyl chain is (CH2)n, n = 1-3, behave as glycine templates giving by treatment with [hydroxy(tosyloxy)iodo]benzene in ethyl acetate cis-1-tosyloxy derivatives. When these compounds contain electron-rich aryl substituents with n = 2, they spontaneously cyclize through intramolecular Friedel-Crafts-type diastereoselective reactions to give penta- or hexacyclic compounds. Otherwise, they give by solvolysis cis-1-alkoxy derivatives, which in a second step, may be cyclized in acid if n = 2, 3. All these reactions must occur through N-acyliminium species in SN1-like mechanisms. 1-Alkoxy-2-arylmethyl derivatives are reluctant to cyclize, giving trans-1-hydroxy compounds as the only isolated reaction products.
