195005-10-8

Basic information

• Product Name: 3-Chloro-N-(diphenyl-phosphinoylmethyl)-N-(4-methoxy-benzyl)-isonicotinamide
• Synonyms: 3-Chloro-N-(diphenyl-phosphinoylmethyl)-N-(4-methoxy-benzyl)-isonicotinamide
• CAS NO: 195005-10-8
• Molecular Weight: 490.926
• Mol File: 195005-10-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Chloro-N-(diphenyl-phosphinoylmethyl)-N-(4-methoxy-benzyl)-isonicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-N-(diphenyl-phosphinoylmethyl)-N-(4-methoxy-benzyl)-isonicotinamide(195005-10-8)
• EPA Substance Registry System: 3-Chloro-N-(diphenyl-phosphinoylmethyl)-N-(4-methoxy-benzyl)-isonicotinamide(195005-10-8)

Safety Data

• Hazardous Substances Data: 195005-10-8(Hazardous Substances Data)

Upstream product

• 88912-27-0 3-chloro-isonicotinic acid 
• 195005-12-0 N-[(diphenylphosphinoyl)methyl]-N-(4-methoxybenzyl)amine 

Relevant articles and documents

An efficient one-pot synthesis of 3-(aryl and alkyl)methylene-1H-isoindolin-1-ones via aryne cyclization and horner reaction of o-(and m-) halogeno-N-phosphorylmethylbenzamide derivatives

A series of 3-(alkyl and aryl)methylene-2,3-dihydro-1H-isoindol-1-one derivatives was synthesized by a one-pot reaction sequence involving lithiation of 2- (or 3-)halogeno-N-phosphoryl-methylbenzamides, cyclization of the aryne intermidiate, metal migration and Horner reaction of the resulting phosphorylated aminocarbanion with selected aromatic and aliphatic aldehydes.