195153-97-0

Upstream product

• 108-91-8 cyclohexylamine 
• 111831-89-1 N-(2-Bromoprop-2-enyl)cyclohexylamine 

Downstream Products

• 1437300-29-2 dimethyl 2-(but-2-yn-1-yl)-2-((1-cyclohexyl-4,5-dimethyl-1H-pyrrol-3-yl)methyl)malonate 
• 1554627-45-0 C₁₉H₂₁N₃ 
• 1438427-21-4 3-cyclohexyl-4-methylene-1-(toluene-4-sulfonyl)-imidazolidin-2-one 
• 1431883-05-4 (3-butyl-4-methyl-3H-thiazol-2-ylidene)-(4-nitro-phenyl)-amine 
• 1147892-74-7 diethyl [3-(cyclohexylamino)-1-phenylhexan-3-yl]phosphonate 
• 112-12-9 methyl nonyl ketone 

Relevant academic research and scientific papers

Nickel-catalyzed [3 + 2] cycloaddition of diynes with methyleneaziridines via C-C bond cleavage

A Ni-catalyzed [3 + 2] cycloaddition via C-C bond cleavage of methyleneaziridines under mild conditions was developed. This reaction gave substituted pyrroles with excellent regioselectivity and a pendant alkyne unit, which is advantageous for further derivatization. The Royal Society of Chemistry 2013.

Observations on the ring opening reactions of 2-methyleneaziridines with acid chlorides and alkyl chloroformates

The ring-opening reactions of 2-methylene-aziridines with acid chlorides and alkyl chloroformates were studied. The mechanism suggested that the reactions proceeded by initial N-acylation to form corresponding aziridinium cation. This was followed by regiospecific ring opening by chloride ion at the sp3 hybridized aziridine carbon atom to produce the observed product.