195191-47-0

Basic information

• Product Name: 2-Bromo-4-chloro-6-fluoroaniline
• Synonyms: 6-BroMo-4-chloro-2-fluoroaniline;2-BROMO-4-CHLORO-6-FLUOROANILINE;2-AMINO-1-BROMO-5-CHLORO-3-FLUOROBENZENE;2-Bromo-4-chloro-6-fluoroaniline 98%;2-Bromo-4-chloro-6-fluoroaniline98%;2-Fluoro-4-Chloro-6-Bromo aniline;2-BROMO-4-CHLORO-6-FLUOROANILINE, 97+%
• CAS NO: 195191-47-0
• Molecular Formula: C6H4BrClFN
• Molecular Weight: 224.46
• Product Categories: Fluorine series;Anilines, Aromatic Amines and Nitro Compounds;Anilines, Amides & Amines;Bromine Compounds;Chlorine Compounds;Fluorine Compounds;Amines;C2 to C6;Nitrogen Compounds
• Mol File: 195191-47-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: 41-43 °C(lit.)
• Boiling Point: 243°Cat760mmHg
• Flash Point: >230 °F
• Appearance: pink to brown solid
• Density: 1.809g/cm³
• Vapor Pressure: 0.033mmHg at 25°C
• Refractive Index: 1.611
• Storage Temp.: Room temperature.
• Solubility: soluble in Methanol
• PKA: 0.51±0.10(Predicted)
• CAS DataBase Reference: 2-Bromo-4-chloro-6-fluoroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-4-chloro-6-fluoroaniline(195191-47-0)
• EPA Substance Registry System: 2-Bromo-4-chloro-6-fluoroaniline(195191-47-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-37/39-36/37/39-24/25
• WGK Germany: 3
• Hazardous Substances Data: 195191-47-0(Hazardous Substances Data)

Usage

Chemical Properties

Pink to brown crystalline solid

Uses

2-Bromo-4-chloro-6-fluoroaniline may be used in the preparation of fragment A of an orally bioavailable and CNS penetrant bradykinin1antagonist.

General Description

2-Bromo-4-chloro-6-fluoroaniline is an aniline derivative.

InChI:InChI=1/C6H4BrClFN/c7-4-1-3(8)2-5(9)6(4)10/h1-2H,10H2

Downstream Products

• 201849-16-3 1-bromo-5-chloro-3-fluoro-2-iodobenzene 
• 937054-31-4 methyl 2-[(4R,6S)-8-chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]acetate 
• 937054-32-5 methyl 2-[(4S,6R)-8-chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6h-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]acetate 
• 937054-36-9 Ethyl 2-(1-{2-[(4S,6R)-8-chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]acetyl}-4-piperidinyl)acetate 
• 937054-35-8 Ethyl 2-(1-{2-[(4R,6S)-8-chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]acetyl}-4-piperidinyl)acetate 
• 937054-37-0 2-(1-{2-[(4R,6S)-8-Chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]acetyl}-4-piperidinyl)acetic acid 
• 937054-38-1 ethyl 2-(2-{2-[(4R,6S)-8-chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]ethyl}-2H-1,2,3,4-tetrazol-5-yl)acetate 
• 937054-47-2 Ethyl 2-(1-{2-[(4R,6S)-8-chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]ethyl}-1H-1,2,4-triazol-3-yl)acetate 
• 937054-46-1 ethyl 2-(1-{2-[(4R,6S)-8-chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]ethyl}-1H-1,2,4-triazol-5-yl)acetate 
• 937054-42-7 2-(2-{2-[(4R,6S)-8-Chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]ethyl}-2H-1,2,3,4-tetrazol-5-yl)acetic acid 
• 937054-48-3 2-(1-{2-[(4R,6S)-8-Chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]ethyl}-1H-1,2,4-triazol-3-yl)acetic acid 
• 937054-51-8 1-{2-[(4R,6S)-8-Chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]ethyl}-1H-1,2,3-triazol-5-carboxylic acid 
• 937054-52-9 1-{2-[(4R,6S)-8-Chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]ethyl}-1H-1,2,3-triazole-4-carboxylic acid 
• 937054-43-8 3-[(4R,6S)-8-Chloro-6-(2,3-dimethoxyphenyl)-10-fluoro-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]propionic acid